両側口角に発症した原発性限局性アミロイドーシスの1例

• Published in: 日本口腔外科学会雑誌 Vol. 58; no. 4; pp. 252 - 256
• Main Authors: 傳田, 祐也, 野池, 淳一, 清水, 武, 五島, 秀樹, 柴田, 哲伸, 横林, 敏夫
• Format: Journal Article
• Language: Japanese
• Published: 社団法人 日本口腔外科学会 20.04.2012
• Subjects: AL蛋白; 原発性限局性アミロイドーシス; 口角
• ISSN: 0021-5163; 2186-1579
• DOI: 10.5794/jjoms.58.252

We report a rare case of bilateral primary localized amyloidosis of the angle of the mouth. A 76-year-old woman presented with bilateral painless soft elastic masses arising in the angles of her mouth. An excisional biopsy was first performed for the right-side mass, followed by the left-side mass 6 months later. The histopathological diagnosis was amyloidosis, with a precursor of Aκ, in association with amyloid L protein deposition. We suspected amyloid deposition in other organs as well as the presence of amyloidosis in association with multiple myeloma. Comprehensive general physical examination revealed no problems, and bilateral primary localized amyloidosis of the angle of the mouth was confirmed.