Urinary tract infection in patients managed by clean intermittent catheterization

• Published in: Japanese Journal of Chemotherapy Vol. 44; no. 12; pp. 874 - 878
• Main Authors: Ohta, Nobutaka, Fujita, Kimio, Suzuki, Kazuo, Nakanishi, Toshimasa, Mutoh, Satoru, Usami, Takatoshi
• Format: Journal Article
• Language: Japanese
• Published: Japanese Society of Chemotherapy 1996; 公益社団法人 日本化学療法学会
• Subjects: 尿路感染症; 間欠的自己導尿
• ISSN: 1340-7007; 1884-5886
• DOI: 10.11250/chemotherapy1995.44.874

This study was undertaken to investigate urinary tract infection (UTI) in patients managed by clean intermittent catheterization. The subjects were 29 patients undergoing clean intermittent catheterization. We investigated the prevalence of infection, the causative organisms, individual background factors, and the oral antimicrobial therapy used. The criteria for diagnosis of urinary tract infection included pyuria of 10 white blood cells per high power field and bacteriuria of ≥105 CFU/ml. Student's t-test was employed for statistical analysis of the results. After an average follow-up period of 28.2 months, 23 of the 29 patients (79%) experienced UTI. Pyuria without bacteriuria occurred 0.15 times per month and UTI occurred 0.07 times per month on average. There was a significantly higher prevalence of UTI in patients with urinary incontinence and a history of an indwelling bladder catheter. New quinolone antimicrobial agents were the most common antibiotics used (65.8%). Escherichia coli was the major causative organism and gram-negative bacilli accounted for 52.9%. Early introduction of clean intermittent catheterization, and proper explanation to both the patient and the family may facilitate UTI prevention.