Antimicrobial susceptibilities of clinically isolated strains of Gardnerella vaginalis

• Published in: Japanese Journal of Chemotherapy Vol. 54; no. 3; pp. 249 - 254
• Main Authors: Yasui, Kumiko, Ishii, Yoshikazu, Murakami, Hinako, Furuya, Nobuhiko, Iwata, Morihiro, Maehara, Chikako, Yamaguchi, Keizo, Matsumoto, Tetsuya, Tateda, Kazuhiro
• Format: Journal Article
• Language: Japanese
• Published: Japanese Society of Chemotherapy 2006; 公益社団法人 日本化学療法学会
• Subjects: antimicrobial susceptibility; Gardnerella vaginalis
• ISSN: 1340-7007; 1884-5886
• DOI: 10.11250/chemotherapy1995.54.249

We investigated the antimicrobial susceptibilities of Gardnerella vaginalis by using 607 strains of clinical isolates at Toho University Omori Medical Center from 2002 to 2004. Minimum Inhibitory Concentrations (MICs) of 17 antimicrobial agents were determined with micro broth dilution methods based on the guidelines of NCCLS. Penicillins, carbapenems, macrolides and glycopeptides antimicrobial agents showed potent activities of which the MIC90 levels were 1 μg/mL or less. We could not find any major differences in the antimicrobial susceptibilities between our results and the results in some previous reports. We therefore insist that we can choose adequate antibiotic regimens for patients with G. vaginalis according to these results. Although we could not find any resistant strains against all antibiotics tested in this study, we think that further investigations should be needed to follow up the antimicrobial susceptibilities of clinical isolates of G. vaginalis.