THE CLINICAL SIGNIFICANCE OF SERUM HAPTOGLOBIN IN EAR, NOSE AND THROAT DISEASES

Heptoglobin (Hp) is a glycoprotein in the α2-globulin fraction, which has a specific affinity for binding with Hb. The biochemical, biological and pathological significance of its affinity to Hb has been studied in 252 subjects consisting of patients with cancer, malignant lymphoma, or inflammatory...

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Published inJIBI INKOKA TEMBO Vol. 20; no. 5; pp. 683 - 688,630
Main Authors KATAURA, Akikatsu, MORIMOTO, Kenji, ENOMOTO, Kazuko, DOI, Yasuyuki
Format Journal Article
LanguageJapanese
Published Society of Oto-rhino-laryngology Tokyo 1977
耳鼻咽喉科展望会
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ISSN0386-9687
1883-6429
DOI10.11453/orltokyo1958.20.683

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Summary:Heptoglobin (Hp) is a glycoprotein in the α2-globulin fraction, which has a specific affinity for binding with Hb. The biochemical, biological and pathological significance of its affinity to Hb has been studied in 252 subjects consisting of patients with cancer, malignant lymphoma, or inflammatory diseases of the ear, nose and throat. Serum haptoglobin level of the cancer patients is found to be higher than that of normal individual, and roughly parallels the serum seromucoid level. Also, it was found that the serum haptoglobin level in acute inflammation is the highest among the various diseases. It was felt that the qualitative measurement of serum haptoblobin values is quite valuable not only as a supplement for diagnosis of malignant neoplasmas but also for diganosis of acute reactionary phase of inflammation.
ISSN:0386-9687
1883-6429
DOI:10.11453/orltokyo1958.20.683