The Case of resected Hepatic Epithelioidhemangio Endothelioma associated with Focal Nodular Hyperplasia and Hepatic Cavernous Hemangioma

• Published in: The Japanese Journal of Gastroenterological Surgery Vol. 44; no. 2; pp. 131 - 137
• Main Authors: Mizukami, Tatsuzo, Kamiyama, Toshiya, Nakanishi, Kazuaki, Yokoo, Hideki, Tahara, Munenori, Fukumori, Daisuke, Kamachi, Hirofumi, Matsushita, Michiaki, Todo, Satoru
• Format: Journal Article
• Language: Japanese
• Published: The Japanese Society of Gastroenterological Surgery 2011
• Subjects: hepatic epithelioid hemangioendothelioma; hepatic tumor; oral contraceptive
• ISSN: 0386-9768; 1348-9372
• DOI: 10.5833/jjgs.44.131

Hepatic epithelioid hemangioendothelioma (EHE), a rarely malignant non epithelial tumor, is often nonresectable, when found, due to multiple bilateral hepatic lobes-hence the few reports of liver resection. We report such a resection in EHE with focal nodular hyperplasia (FNH) and hepatic cavernous hemangioma (HCH). A normally healthy 44-year-old woman, taking oral contraceptives for many years in October 2008, was found in a medical checkup to have liver dysfunction. Abdominal ultrasonography (US) indicated multiple tumors, but computed tomography (CT) and magnetic resonance imaging (MRI) results were inconclusive. Liver biopsy indicated EHE and she was referred for treatment potentially including liver transplantation. Right hepatic lobectomy and partial S2, 3, and 4 resection were done in February 2009. Histopathologically, findings included EHE, HCH, and FNH. In so far as a search of the literature indicated, only one other such case has been reported.