PRANLUKAST AND BEPOTASTINE BESILATE PRODUCES BENEFICIAL EFFECTS ON PATIENTS WITH POLLINOSIS

• Published in: JIBI INKOKA TEMBO Vol. 49; no. 1; pp. 18 - 23
• Main Authors: Araki, Susumu, Nakamura, Mari, Yamaguchi, Tarou, Hasegawa, Tatsuya, Suzuki, Mamoru
• Format: Journal Article
• Language: Japanese
• Published: Society of Oto-rhino-laryngology Tokyo 2006; 耳鼻咽喉科展望会
• Subjects: allergic rhinitis; early treatment; field research; pollinosis; アレルギー性鼻炎; スギ花粉症; 季節前投与; 野外比較試験
• ISSN: 0386-9687; 1883-6429
• DOI: 10.11453/orltokyo1958.49.18

We investigated the usefulness of the early treatment of pollinosis with Pranlukast and Bepotastine besilate and Beclometasone through a field research approach. We compared the effects of the combination therapy with Pranlukast and Bepotastine besilate and Beclometasone in the season of mass scatter. At the beginning and final session of the field research, there was no significant difference in eosinophilic cationic protein levels, the ventilation of the nasal cavity and visual analog scale evaluation of sneezing, runny nose or daily life. There were some significant differences in the score of sneezing, stuffy nose and daily life and the generalization of the JRQLQ #1 (Japan Rhinoconjunctivitis Quality of Life Questionaire) between the combination therapy with Pranlukast and Bepotastine besilate and the therapy with Beclometasone alone. The early treatment with any medicine for allergic rhinitis had a possibly useful function. The combination therapy with Pranlukast and Bepotastine besilate was more useful for improving the subjective symptoms than the therapy with Beclometasone alone.