COMPUTED TOMOGRAPHY (CT) FINDINGS OF SCHIZOPHRENIC PATIENTS AFTER LONG TIME FROM PSYCHOSURGERY

• Published in: Japanese Journal of National Medical Services Vol. 45; no. 11; pp. 1021 - 1026
• Main Authors: OGASHIWA, Motohide, MURAKAMI, Hiroshi, ADACHI, Naoto, AKASHI, Toshio, TOYODA, Junzou
• Format: Journal Article
• Language: Japanese
• Published: Japanese Society of National Medical Services 1991; 一般社団法人 国立医療学会
• Subjects: brain atrophy; computed tomography (CT); CT; long-term outcome; psychosurgery; scizophrenia; 精神分裂病; 精神外科; 脳萎縮; 長期予後
• ISSN: 0021-1699; 1884-8729
• DOI: 10.11261/iryo1946.45.1021

The CT findings on 20 chronic schizophrenic inpatients who had undergone psycho-surgery 37 years ago (operated group) were compared to 20 chronic schizophrenic inpa-tients without psychosurgery (non-operated group). The subjects of non-operated group were selected by matched age, sex and duration of the illness. Operated group showed significant decrease in frontal lobe size (p<0.001), enlargement of frontal horns of the lateral ventricle (p<0.01), widening of interhemispheric fissure (p<0.05) and brain atrophy (p<0.001) in comparison with non-operated group. Size of surgical injury showed significant rank correlation to frontal lobe size (p<0.01) and brain atrophy (p<0.001). Regarding the horizontal level of injury, in comparison with non-operated group, the patients with deficit in higher frontal areas showed enlargement of lateral ventricles (p<0.01) and those with deficit in lower frontal areas showed widening of interhemispheric fissure (p<0.05). Regarding the laterality of injury, the patients with deficit in left hemisphere showed significantly widened sylvian fissure in comparison with non-operated group (p<0.05).