Development of a New Vascular Graft for Hemodialysis

We developed a new vascular graft for hemodialysis, which consists of three layers: inner and outer layers made of highly porous membrane to provide for sufficient tissue anchoring, and a middle layer made of non-porous elastomer with strong sealing characteristics. In this study, we examined the gr...

Full description

Saved in:
Bibliographic Details
Published inJinko Zoki Vol. 29; no. 1; pp. 245 - 248
Main Authors Kazuno, K, Takano, Y, Ezaki, Y
Format Journal Article
LanguageJapanese
Published JAPANESE SOCIETY FOR ARTIFICIAL ORGANS 2000
Subjects
blood access
durability
hemodialysis
resealability
vascular graft
Online AccessGet full text

Cover

More Information
Summary:We developed a new vascular graft for hemodialysis, which consists of three layers: inner and outer layers made of highly porous membrane to provide for sufficient tissue anchoring, and a middle layer made of non-porous elastomer with strong sealing characteristics. In this study, we examined the graft's kinking, tensile, and burst strengths, and leakage due to puncture holes using the ePTFE graft as a control. In vitro study showed that the new graft efficiently resealed itself after removal of a needle and demonstrated high durability after repeated punctures in comparison with the control graft. In a canine arteriovenous shunt model, the new graft revealed not only the ability to seal needle puncture sites with minimal compression time but the ability to prevent bleeding. These properties showed that this new graft could be a novel alternative to conventional artificial grafts for hemodialysis.
ISSN:0300-0818
1883-6097
DOI:10.11392/jsao1972.29.245