ANALYSIS OF FATTY LIVER BY CT VALUES IN OBESE CHILDREN

• Published in: Japanese Journal of National Medical Services Vol. 50; no. 6; pp. 425 - 429
• Main Authors: NAGANUMA, Yoshihiro, UCHIYAMA, Makoto, OZAWA, Kanzi, TOHYAMA, Jun, TOMIZAWA, Shuichi, IKARASHI, Kozo
• Format: Journal Article
• Language: Japanese
• Published: Japanese Society of National Medical Services 1996; 一般社団法人 国立医療学会
• Subjects: CT; fatty liver; liver dysfunction; obesity; therapy; 治療; 肝機能障害; 肥満; 脂肪肝
• ISSN: 0021-1699; 1884-8729
• DOI: 10.11261/iryo1946.50.425

Liver attenuation values were measured by CT in 97 (183 times) obese children with ages 3 to 18 years and a diagnosis of fatty liver was made in 42 subjects. Liver/spleen ration from CT measurements showed a significant negative correlation with the percentage of standard body weight, and with the systolic pressure. In children with fatty liver, systolic pressure and serum GOT, GPT, ChE, TC, TG, ApoB and insulin were significantly higher than those in children without fatty liver. After a low-calorie dietary regimen and exercise therapy, the liver/spleen ratio and GPT improved in all children. The diagnosis of fatty infiltration (fatty liver) was made with a liver/spleen ratio of less than 1.0 as determined by the number of measurements taken, a reasonable criterion for the diagnosis of fatty liver by CT in children. There were some children with elevated GPT who showed normal CT findings. This may be caused by overnutrition which was associated with fatty infiltration, since GPT decreased in all these children after treatment. The present study suggests that CT is a useful procedure in diagnosing fatty liver, and in monitoring and determining efficacy of treatment in obese children.