PHYSIOLOGICAL ACCOMMODATION PROCESS OF EXPERIMENTAL ANIMALS TO SYSTEMIC NONPULSATILE FLOW

A pulsatile left ventricular assist device was quickly replaced by a centrifugal pump without anesthesia in 5 goats 2 weeks after surgery. A 100% bypass of nonpulsatile systemic flow was immediately obtained and the pump was controlled to maintain the same mean aortic pressure as before the switch....

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Published inJinko Zoki Vol. 20; no. 3; pp. 823 - 828
Main Authors TAENAKA, Y, TATSUMI, E, SAKAKI, M, SASAKI, E, NAKATANI, T, AKAGI, H, SEKII, H, YAGURA, A, GOTO, M, MASUZAWA, T, MATSUO, Y, INOUE, K, TAKANO, H
Format Journal Article
LanguageJapanese
Published JAPANESE SOCIETY FOR ARTIFICIAL ORGANS 1991
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Summary:A pulsatile left ventricular assist device was quickly replaced by a centrifugal pump without anesthesia in 5 goats 2 weeks after surgery. A 100% bypass of nonpulsatile systemic flow was immediately obtained and the pump was controlled to maintain the same mean aortic pressure as before the switch. Central venous pressure, cardiac output, systemic vascular resistance, oxygen consumption, blood lactate, and plasma adrenalin, noradrenalin, renin activity, angiotensin II and aldosterone did not deviate from the control levels.
ISSN:0300-0818
1883-6097
DOI:10.11392/jsao1972.20.823