A NOVEL METHOD FOR THE MANUFACTURE OF SURGICAL MATERIALS FROM EXTRACTED COLLAGEN ALONE WITH STRONG MECHANICAL PROPERTIES FOR SUTURING

• Published in: Jinko Zoki Vol. 28; no. 1; pp. 211 - 216
• Main Authors: Matumoto, K, Ueda, H, Sekine, T, Yamamoto, Y, Kiyotani, T, Takimoto, Y, Nakamura, T, Shimizu, Y
• Format: Journal Article
• Language: Japanese
• Published: JAPANESE SOCIETY FOR ARTIFICIAL ORGANS 01.01.1999
• Subjects: collagen; manufacturing methods; mechanical strength; surgical materials
• ISSN: 0300-0818; 1883-6097
• DOI: 10.11392/jsao1972.28.211

We have developed a novel manufacturing method for surgical materials with a high degree of mechanical. strength. The final materials were made from extracted collagen alone. Using this method, we made three types of surgical membranes. The base membranes were made from freeze-dried collagen solution in a cast. Membrane A was made from this base membrane. Coating procedures with collagen solution were supplemented to both surfaces of a pressed base membrane. Membrane B1: A base membrane is soaked in collagen solution and heat treatment in vacuo and compression was added. Membrane B2: The soaking procedures were carried out twice on a base membrane and it was then pressed. All membranes were heated in vacuo as a final heat treatment. Microstructural observation showed that the surfaces of Membrane A were coated with dense amorphous collagen layers and that B1 and B2 increased in the number of collagen layer piles. Though Membrane B1 did not have strong enough mechanical properties to resist being cut by a suture under wet conditions, Membrane A and B2 did have sufficient strength to resist cutting. Because our manufacturing method is easy and not costly, it is applicable for various surgical materials.