Effects of Opioid Peptides Administered in Conscious Rats on the Changes in Blood Adrenaline Levels Caused by Immobilization Stress

Effects of several opioid peptides administered in the lateral cerebroventricle on the changes in blood adrenaline (AD) levels were examined at 10, 20 and 30 min after the start of immobilization in conscious rats. β-Endorphin, (D-Ala2)-Met-enkephalinamide, morphiceptin and (D-Ala2, D-Leu5)-enkephal...

Full description

Saved in:
Bibliographic Details
Published inThe Japanese Journal of Pharmacology Vol. 50; no. 3; pp. 354 - 356
Main Authors NAKAMURA, Mikio, KAMATA, Kunie, INOUE, Hakubun, INABA, Minoru
Format Journal Article
LanguageEnglish
Published The Japanese Pharmacological Society 1989
Online AccessGet full text

Cover

More Information
Summary:Effects of several opioid peptides administered in the lateral cerebroventricle on the changes in blood adrenaline (AD) levels were examined at 10, 20 and 30 min after the start of immobilization in conscious rats. β-Endorphin, (D-Ala2)-Met-enkephalinamide, morphiceptin and (D-Ala2, D-Leu5)-enkephalinamide produced significantly lower elevations of AD than the control, and the effect was enhanced by naloxone. The effect of dynorphin, however, was almost the same as that of the control.
ISSN:0021-5198
1347-3506
DOI:10.1254/jjp.50.354