CLINICAL INVESTIGATIONS OF CS-1170 IN SURGICAL FIELD
1. Consecutive transfer of CS-1170 in bile was investigated on 2 groups of patients, the one with disorder of hepatic function and the other without these disorders. 2. In the group of normal hepatic function, concentrations of the drug showed a peak of more than 20 μg/ml after 1 g drip infusion, wh...
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| Published in | CHEMOTHERAPY Vol. 26; no. Supplement5; pp. 430 - 434 |
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| Main Author | |
| Format | Journal Article |
| Language | Japanese |
| Published |
Japanese Society of Chemotherapy
1978
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| Online Access | Get full text |
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| Summary: | 1. Consecutive transfer of CS-1170 in bile was investigated on 2 groups of patients, the one with disorder of hepatic function and the other without these disorders. 2. In the group of normal hepatic function, concentrations of the drug showed a peak of more than 20 μg/ml after 1 g drip infusion, while a peak of 35.5 μg/ml after 2 g drip infusion. 3. In the group of disordered hepatic function, scattering was noticed from 4.2 μg/ml to 2 μg/ml after 1 g drip infusion. 4. CS-1170 was drip infused to 5 cases of biliary tract infection at a daily dose of 4 g divided into 2 times, and the results obtained were remarkably effective in 3 cases, effective in 1 case and ineffective in 1 case. No side effect was observed with the drug throughout all cases. |
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| ISSN: | 0009-3165 1884-5894 |
| DOI: | 10.11250/chemotherapy1953.26.Supplement5_430 |