CLINICAL EXPERIENCE OF CEFMENOXIME (SCE-1365) IN CHRONIC COMPLICATED URINARY TRACT INFECTION

Cefmenoxime (CMX, SCE-1365, ) a new synthetic cephalosporin, was administered to 51 hospitalized patients who were diagnosed as chronic complicated urinary tract infection in the Department of Urology at Kyushu University Hospital and 11 other hospitals, 1g or 2g of cefmenoxime was administered intr...

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Published inCHEMOTHERAPY Vol. 29; no. Supplement1; pp. 877 - 887
Main Author NAKAMUTA, SEIICHI
Format Journal Article
LanguageEnglish
Japanese
Published Japanese Society of Chemotherapy 1981
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Summary:Cefmenoxime (CMX, SCE-1365, ) a new synthetic cephalosporin, was administered to 51 hospitalized patients who were diagnosed as chronic complicated urinary tract infection in the Department of Urology at Kyushu University Hospital and 11 other hospitals, 1g or 2g of cefmenoxime was administered intravenously for 5 days. Clinical evaluations were made in 40 patients by the 2nd Edition of Judgement of UTI Criteria. The clinical effect of cefmenoxime was evaluated to be excellent 9 patients, good in 15 patients and poor in 16 patients. Overall effectiveness rate was 60 per cent in this study. Bacteriologically, 35 strains out of 48 strains disappeared, especially. 7 of 8 strains of Serratia were disappeared, while all 2 strains of Pseudomonas cepacia and 5 of 6 strains of Pseudomonas aeruginosa were persisted after treatment of cefmenoxime. No side effect of this drug was noticed in any patients.
ISSN:0009-3165
1884-5894
DOI:10.11250/chemotherapy1953.29.Supplement1_877