A Case of Severe Acute Hepatorenal Failure due to Aeromoas hydrophila Septicemia

• Published in: Kansenshogaku Zasshi Vol. 70; no. 10; pp. 1111 - 1115
• Main Authors: YOKOBA, Masanori, SHIRASAKI, Keiji, AOKI, Noriaki, SOMA, Kazui
• Format: Journal Article
• Language: Japanese
• Published: Japan The Japanese Association for Infectious Diseases 01.10.1996
• Subjects: Aeromonas hydrophila; alcoholic liver fibrosis; Bacteremia - complications; Fatal Outcome; Gram-Negative Bacterial Infections - complications; Hepatorenal Syndrome - etiology; Humans; Male; Middle Aged; septicemia
• ISSN: 0387-5911; 1884-569X
• DOI: 10.11150/kansenshogakuzasshi1970.70.1111

A case of septicemia due to Aeromonas hydrophila (A. hydrophila) in a 54-year-old male suffering from progressive severe jaundice and fatigue is reported. The patient developed multiple organ failure despite aggressive therapy including plasma exchange and glucose-insulin therapy. Upon admission to our hospital, therapy was started with ampicillin (ABPC) 4 g/day, gentamicin (GM) 120 mg/day, hemodialysis, continuous hemofiltration, catecholamines and a respirator, but he expired on the 2nd hospital day. Blood culture and histology revealed A. hydrophila. Postomortern examination showed alcoholic liver fibrosis which was most likely liver cirrhosis. In the literature, patients with septicemia due to Aeromonas had underlying hepatic cirrhosis more often than did those with septicemia due to other gram-negative bacilli. Therefore, it is important to consider the possibility of liver cirrhosis in patients with A. hydrophila septicemia.