Researches on Ergot Fungus Part 21. Production of Ergot Alkaloids in Surface Replacement Cultures (1)

• Published in: Nippon Nōgeikagaku Kaishi Vol. 27; no. 9; pp. 613 - 617
• Main Authors: ABE, Matazo, YAMANO, Togo, KUSUMOTO, Mitsugi
• Format: Journal Article
• Language: English; Japanese
• Published: Japan Society for Bioscience, Biotechnology, and Agrochemistry 1953
• ISSN: 0002-1407; 1883-6844
• DOI: 10.1271/nogeikagaku1924.27.613

(1) A large amount of ergot alkaloids is produced within appreciable short times in surface replacement cultures. (2) The ergot alkaloids are not produced when the growth of the fungus does not take place even in surface replacement cultures. (3) The alkaloid production in surface replacement cultures is not so much affected by the natures of C- or N-sources as in the ordinary surface cultures, as long as the age of mycelium is not so young or so old and the depth of the culture liquid is not so high. 4) The surface mycelium of ergot fungus continues to produce the alkaloids with undi-minished vigor through several successive replacement of culture liquids. The alkaloid production in this semi-continuous process fundamentally depends upon the surface mycelium first obtained. (5) The ergot alkaloid production in surface replacement cultures is much affected by the age of mycelium or by the depth of the replacement liquid.