Mass screening for prostate cancer in Ikeda City Osaka

• Published in: Nippon Hinyokika Gakkai zasshi Vol. 97; no. 6; p. 791
• Main Authors: Tsutahar, Koichi, Yokoyama, Shohei, Fukuhara, Shinichiro, Mori, Naoki, Hara, Tsuneo, Yamaguchi, Seiji, Kitamura, Kenya, Kajimoto, Masaaki
• Format: Journal Article
• Language: Japanese
• Published: Japan 01.09.2006
• Subjects: Aged; Aged, 80 and over; Biomarkers, Tumor - blood; Humans; Japan; Male; Mass Screening; Middle Aged; Prostate-Specific Antigen - blood; Prostatic Neoplasms - diagnosis; Prostatic Neoplasms - prevention & control; Japan
• ISSN: 0021-5287
• DOI: 10.5980/jpnjurol1989.97.791

Screening with prostate specific antigen (PSA) to detect prostate cancer was started in Ikeda City Osaka from 2003 as part of the city's health program. We evaluated the first year's result. Fifty-year-old or elder men living in Ikeda City who wanted to have their serum PSA level (Tandem-R) measured to screen for prostate cancer was entered into the screening program. Men whose PSA levels detected to exceed 4.1 ng/ml were told they should visit a urologist for further examinations to detect possible prostate cancer. These examinations included prostate biopsy. The results of further examinations were reported to Ikeda City and evaluated. The population of fifty-years-old or elder men in Ikeda City was 18,161. 3738 (21.0%) men had their serum PSA levels measured. 367 (9.81%) of the men were told they should undergo further examinations to detect possible prostate cancer. 263 (71.7%) men visited a urologist for further examinations, and prostate biopsy was performed in 138 (52.5%) of them. Among these 138, prostate cancer diagnosed in 91 (65.9%). The positive rate of prostate biopsy was 65.9% (91/138), The detection rate for prostate cancer was therefore 2.43% (91/3738). Patient's numbers for each clinical stage were 57 (62.6%) in B, 30 (32.9%) in C, 4 (4.4%) in D. Prostate cancer was diagnosed in 2.34% of 3738 men who had their serum PSA levels measured, and in stage B two thirds had a positive diagnosis. PSA screening to detect prostate cancer as one of the health checks in Ikeda City was useful in detecting early prostate cancer.