CLINICAL STUDIES OF CEFOTAXIME ON INFECTIONS IN INTERNAL MEDICINE
Clinical studies on a new cephalosporin antibiotic, cefotaxime (CTX) were carried out in 79 patients with various types of infections in internal medicine. The efficacy rates were 65.8% in 39 cases of respiratory tract infections, 94.1% in 17 cases of biliary tract infections, 75.0% in 12 cases of u...
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Published in | Japanese journal of antibiotics Vol. 37; no. 9; pp. 1714 - 1728 |
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Main Authors | , , , , , , , , , , , |
Format | Journal Article |
Language | Japanese |
Published |
Japan
Japan Antibiotics Research Association
01.09.1984
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Subjects | |
Online Access | Get full text |
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Summary: | Clinical studies on a new cephalosporin antibiotic, cefotaxime (CTX) were carried out in 79 patients with various types of infections in internal medicine. The efficacy rates were 65.8% in 39 cases of respiratory tract infections, 94.1% in 17 cases of biliary tract infections, 75.0% in 12 cases of urinary tract infections, 80.0% in 11 cases of other infections, and 75.3% in all cases. After CTX therapy, body temperature was improved in 76.7% of all 79 patients, particularly being excellent in all cases of biliary tract infections. Furthermore, symptoms such as cough, dyspnea, chest pain, moist rale and anorexia were improved to a great degree after CTX therapy. Adverse reactions and abnormal laboratory findings consisted of mild liver injury in 1 out of 79 cases. CTX was assessed to be an effective antibiotic for various types of infections in internal medicine. |
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ISSN: | 0368-2781 2186-5477 |
DOI: | 10.11553/antibiotics1968b.37.1714 |