Adult case of hypoganglionosis of the colon with a skip lesion: a case report

A 77-year-old woman was referred for severe constipation and abdominal distension which had lasted for 1 month. A computed tomography (CT) scan and a colonoscopy revealed segmental stricture in the transverse and descending colons. After no improvement in her symptoms was observed with conservative...

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Bibliographic Details
Published inNippon Shōkakibyō Gakkai zasshi Vol. 117; no. 3; p. 237
Main Authors Watahiki, Yu, Suzuki, Tomohiro, Koya, Yudai, Matsuoka, Naoki, Matsuhashi, Nobuo, Ichii, Osamu, Tai, Mayumi, Ejiri, Yutaka, Ohira, Hiromasa
Format Journal Article
LanguageJapanese
Published Japan 2020
Subjects
Aged
Colectomy
Colon - innervation
Female
Humans
Myenteric Plexus
Recurrence
Tomography, X-Ray Computed
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Summary:A 77-year-old woman was referred for severe constipation and abdominal distension which had lasted for 1 month. A computed tomography (CT) scan and a colonoscopy revealed segmental stricture in the transverse and descending colons. After no improvement in her symptoms was observed with conservative therapy, we performed a left hemicolectomy. Histopathological examination revealed a reduction in ganglion cells in the Meissner's and Auerbach's plexuses and hypoganglionosis was diagnosed. In addition, a diagnosis of acquired hypoganglionosis was made because this case was adult onset, and there has been no recurrence.
ISSN:0446-6586
DOI:10.11405/nisshoshi.117.237