症例 PTCR時に遭遇した右冠動脈左バルサルバ洞起始に合併した若年性心筋梗塞の1例
最近心筋梗塞急性発症期に,PTCR(経皮経管冠動脈再疎通術)を行い,梗塞壊死部を最少限度に抑える治療が確立されてきた.我々は胸痛を主症状とした若年発症心筋梗塞患者の急性発症期にPTCRを企てたが,責任冠動脈を発見できず,慢性期の左バルサルバ洞造影にて,右冠動脈左バルサルバ洞起始異常の合併症として心筋梗塞が発症したと診断し得た症例を経験した. 従来右冠動脈起始異常は臨床的意義は乏しいとされていたが,最近は重症度は,異常冠動脈の支配する心筋領域の広さに依存するという報告がされており,本例はその説を支持するものであると思われた.また,本例のような起始異常は極めてまれであり,心筋梗塞を合併した報告はあ...
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Published in | 心臓 Vol. 19; no. 9; pp. 1110 - 1116 |
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Language | Japanese |
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公益財団法人 日本心臓財団
1987
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ISSN | 0586-4488 2186-3016 |
DOI | 10.11281/shinzo1969.19.9_1110 |
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Abstract | 最近心筋梗塞急性発症期に,PTCR(経皮経管冠動脈再疎通術)を行い,梗塞壊死部を最少限度に抑える治療が確立されてきた.我々は胸痛を主症状とした若年発症心筋梗塞患者の急性発症期にPTCRを企てたが,責任冠動脈を発見できず,慢性期の左バルサルバ洞造影にて,右冠動脈左バルサルバ洞起始異常の合併症として心筋梗塞が発症したと診断し得た症例を経験した. 従来右冠動脈起始異常は臨床的意義は乏しいとされていたが,最近は重症度は,異常冠動脈の支配する心筋領域の広さに依存するという報告がされており,本例はその説を支持するものであると思われた.また,本例のような起始異常は極めてまれであり,心筋梗塞を合併した報告はあるものの,PTCR時にかような例に遭遇したという報告は,本邦では筆者の調べる限りではない.しかし,PTCRが普及するにつれて,かような症例の報告は増えると思われ,若干の文献的考察を加え,遭遇時の警鐘の意味を含めて報告する. |
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AbstractList | 最近心筋梗塞急性発症期に,PTCR(経皮経管冠動脈再疎通術)を行い,梗塞壊死部を最少限度に抑える治療が確立されてきた.我々は胸痛を主症状とした若年発症心筋梗塞患者の急性発症期にPTCRを企てたが,責任冠動脈を発見できず,慢性期の左バルサルバ洞造影にて,右冠動脈左バルサルバ洞起始異常の合併症として心筋梗塞が発症したと診断し得た症例を経験した. 従来右冠動脈起始異常は臨床的意義は乏しいとされていたが,最近は重症度は,異常冠動脈の支配する心筋領域の広さに依存するという報告がされており,本例はその説を支持するものであると思われた.また,本例のような起始異常は極めてまれであり,心筋梗塞を合併した報告はあるものの,PTCR時にかような例に遭遇したという報告は,本邦では筆者の調べる限りではない.しかし,PTCRが普及するにつれて,かような症例の報告は増えると思われ,若干の文献的考察を加え,遭遇時の警鐘の意味を含めて報告する. |
Author | 小川, 拓男 荒木, 登 保浦, 賢三 中川, 浩 望月, 盈宏 岡本, 浩 阿部, 稔雄 服部, 和樹 |
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References | 21) Thompson, S. I., Vieweg, W. V., Alpert, J. S. et al.: Anomalous origin of the right coronary artery from the left sinus of Valsalva with associated chest pain, report of two cases, Cathet. Cardiovasc, Diag., 2: 397, 1976. 2)神原啓文, ほか: 急性心筋梗塞における選択的ウロキナーゼ注入療法の有効性に関する検討-多施設アンケート調査-. 最新医学, 39: 1059, 1984. 8) Kimbrins, D., Iskandrian, A., Segel, B. L. et al.: Anomalous aortic origin of coronary arteries, Circulation, 58: 606, 1978. 20) Bloomfield, P., Erhlich, C., Folland, E. D. et al.: Anomalous right coronary artery: a surgically correctable cause of angina pectoris. Am. J. Cardiol., 51: 1235, 1983. 26) Liberthson, R. R., Dinsmore, R. E. and Fallon, J. T.: Aberrant coronary artery origin from the aorta. Circulation, 59: 748, 1979. 11) Warren, S. E., Alpert, J. S. and Vieweg, V. R.: Normal single coronary artery and myocardial infarction. Chest, 72: 540, 1977. 28) Schwarts, L., Aldrige H. E., Corol Szarga, M. B. et al.: Percutaneus transluminal angioplasty of an anomalous left circumflex coronary artery arising from the right sinus of Valsalva. Cathet. Cardiovasc. Diag., 8: 623, 1982. 3) Edwards, J. E.: Anomalous coronory arteries with special reference to arteriovenous-like communication. Circulation, 17: 1001, 1958. 19) Brandt, B. III, Martins, J. and Marcus, M. L.: Anomalous origin of the right coronary artery from the left sinus of Valsalva N. Engl, J. Med., 309: 596, 1983. 1) Rentrop, P. et al.: Acute myocardial infarction: intracoronary application of nitroglycerin and streptokinase in combination with transluminal recanalization. Clin. Cardiol., 5: 353, 1979. 15) Jokl, E., Maclellen, J. T., Williams, W. C. et al: Congenital anomaly of left coronary artery in young athletes. Cardiologia, 49: 253, 1966. 23)神吉 豊, 大賀興一, 中村昭光, ほか: 大動脈弁閉鎖不全症を伴った右冠動脈起始異常症の1症例. 日胸外会誌30: 1477, 1982. 16) Chaitman, B. R., Bourassa, MG., Lesprance, J. et al: Aberrant course of the left anterior descending coronary artery associated with anomalous left circumflex origin from the pulmonary artery. Circulation, 52: 955, 1975. 22)吉野公明, 舟津敏朗, 斉木茂樹, ほか: 左バルサルバ洞より発する右冠動脈起始異常の1例. 呼と循, 28: 541, 1980. 6) Engel, H. J., Torres, C. and Page, H. L.: Major variations in anatomical origin of the coronary arteries: angiographic observations in 4, 250 patients without associated congenital heart disease. Cathet. Cardiovasc. Diag., 1: 157, 1975. 17) Sharbaugh, A. H. and White, R. S.: Single coronary artery. analysis of the report of five cases. J. A. M. A., 230: 243, 1974. 5) Chaitman, B. R., Lesprance, J., Saltiel, J., et al.: Clinical, angiographic, and hemodynamic findings in patients with anomalous origin of the coronary arteries. Circulation, 53: 122, 1976. 12) Benson, P. A. and Mateo, S.: Anomalous aortic origin of coronary artery with sudden death, case report and review. Am. Heart J., 79 254, 1970. 7) Robert, E. Hobbs, H. D, Millit, Prakash, V. Raghvan et al.: Congenital coronary artery anomalies: clinical and therapeutic implications. Cardiovasc. Clin., 12: 43, 1981. 13) Choen, L. S. and Shaw, L. D.: Fatal myocardial infarction in an 11-year old boy associated with a unique coronary artery anomary. Am. J. Cardiol., 19: 420, 1967. 10) Cheitlin, M. D., Castro C. M. and Mcallister H. A.: Sudden death as a complication of anoma- lous left coronary origin from the anterior sinus of Valsalva. Circulation, 50: 780, 1974. 14) Liberthson, R. R. Gang, D. L. and Custer, J.: Sudden death in an infant with aberrant origin of the right coronary artery from the left sinus of Valsalva of the aorta, case report and review of the literature Fed. Cardiolo., 4: 45, 1983. 18) Benge, W., Martins, J. B. and Funk, D. C.: Morbidity associated with anomalous origin of the right coronary artery from the left sinus of Valsalva. Am. Heart J., 99: 96, 1980. 4) Ogden, J. A.: Congenital anomalies of the coronary arteries. Am. J. Cardiol., 25: 474, 1970. 9) Liberthson, R. R., Dinsmore, R. E., Bharati, S. et al.: Aberrant coronary artery origin from the aorta. Circulation, 50: 774, 1974. 25)楠目 修, 浜重直久, 土居義典, ほか: 異型狭心症, 前壁心筋梗塞を伴った右冠動脈左バルサルバ洞起始症の1例. 心臓, 16: 1261, 1984. 24)本田俊雄, 風谷幸男, 大門史佳, ほか: 肥大型心筋症と右冠状動脈起始異常とが合併した1症例.心臓, 16: 79, 1984. 27) Als, A. V., Malagold, M., Markins, J. E. et al.: Saccessful streptokinase treatment of a thrombosed, ectopic coronary artery: a case of report. Cardiovasc. Intervent. Radiol., 5: 197, 1982. |
References_xml | – reference: 18) Benge, W., Martins, J. B. and Funk, D. C.: Morbidity associated with anomalous origin of the right coronary artery from the left sinus of Valsalva. Am. Heart J., 99: 96, 1980. – reference: 25)楠目 修, 浜重直久, 土居義典, ほか: 異型狭心症, 前壁心筋梗塞を伴った右冠動脈左バルサルバ洞起始症の1例. 心臓, 16: 1261, 1984. – reference: 15) Jokl, E., Maclellen, J. T., Williams, W. C. et al: Congenital anomaly of left coronary artery in young athletes. Cardiologia, 49: 253, 1966. – reference: 3) Edwards, J. E.: Anomalous coronory arteries with special reference to arteriovenous-like communication. Circulation, 17: 1001, 1958. – reference: 23)神吉 豊, 大賀興一, 中村昭光, ほか: 大動脈弁閉鎖不全症を伴った右冠動脈起始異常症の1症例. 日胸外会誌30: 1477, 1982. – reference: 16) Chaitman, B. R., Bourassa, MG., Lesprance, J. et al: Aberrant course of the left anterior descending coronary artery associated with anomalous left circumflex origin from the pulmonary artery. Circulation, 52: 955, 1975. – reference: 5) Chaitman, B. R., Lesprance, J., Saltiel, J., et al.: Clinical, angiographic, and hemodynamic findings in patients with anomalous origin of the coronary arteries. Circulation, 53: 122, 1976. – reference: 1) Rentrop, P. et al.: Acute myocardial infarction: intracoronary application of nitroglycerin and streptokinase in combination with transluminal recanalization. Clin. Cardiol., 5: 353, 1979. – reference: 10) Cheitlin, M. D., Castro C. M. and Mcallister H. A.: Sudden death as a complication of anoma- lous left coronary origin from the anterior sinus of Valsalva. Circulation, 50: 780, 1974. – reference: 12) Benson, P. A. and Mateo, S.: Anomalous aortic origin of coronary artery with sudden death, case report and review. Am. Heart J., 79 254, 1970. – reference: 19) Brandt, B. III, Martins, J. and Marcus, M. L.: Anomalous origin of the right coronary artery from the left sinus of Valsalva N. Engl, J. Med., 309: 596, 1983. – reference: 26) Liberthson, R. R., Dinsmore, R. E. and Fallon, J. T.: Aberrant coronary artery origin from the aorta. Circulation, 59: 748, 1979. – reference: 27) Als, A. V., Malagold, M., Markins, J. E. et al.: Saccessful streptokinase treatment of a thrombosed, ectopic coronary artery: a case of report. Cardiovasc. Intervent. Radiol., 5: 197, 1982. – reference: 21) Thompson, S. I., Vieweg, W. V., Alpert, J. S. et al.: Anomalous origin of the right coronary artery from the left sinus of Valsalva with associated chest pain, report of two cases, Cathet. Cardiovasc, Diag., 2: 397, 1976. – reference: 22)吉野公明, 舟津敏朗, 斉木茂樹, ほか: 左バルサルバ洞より発する右冠動脈起始異常の1例. 呼と循, 28: 541, 1980. – reference: 2)神原啓文, ほか: 急性心筋梗塞における選択的ウロキナーゼ注入療法の有効性に関する検討-多施設アンケート調査-. 最新医学, 39: 1059, 1984. – reference: 8) Kimbrins, D., Iskandrian, A., Segel, B. L. et al.: Anomalous aortic origin of coronary arteries, Circulation, 58: 606, 1978. – reference: 17) Sharbaugh, A. H. and White, R. S.: Single coronary artery. analysis of the report of five cases. J. A. M. A., 230: 243, 1974. – reference: 11) Warren, S. E., Alpert, J. S. and Vieweg, V. R.: Normal single coronary artery and myocardial infarction. Chest, 72: 540, 1977. – reference: 7) Robert, E. Hobbs, H. D, Millit, Prakash, V. Raghvan et al.: Congenital coronary artery anomalies: clinical and therapeutic implications. Cardiovasc. Clin., 12: 43, 1981. – reference: 24)本田俊雄, 風谷幸男, 大門史佳, ほか: 肥大型心筋症と右冠状動脈起始異常とが合併した1症例.心臓, 16: 79, 1984. – reference: 14) Liberthson, R. R. Gang, D. L. and Custer, J.: Sudden death in an infant with aberrant origin of the right coronary artery from the left sinus of Valsalva of the aorta, case report and review of the literature Fed. Cardiolo., 4: 45, 1983. – reference: 4) Ogden, J. A.: Congenital anomalies of the coronary arteries. Am. J. Cardiol., 25: 474, 1970. – reference: 9) Liberthson, R. R., Dinsmore, R. E., Bharati, S. et al.: Aberrant coronary artery origin from the aorta. Circulation, 50: 774, 1974. – reference: 20) Bloomfield, P., Erhlich, C., Folland, E. D. et al.: Anomalous right coronary artery: a surgically correctable cause of angina pectoris. Am. J. Cardiol., 51: 1235, 1983. – reference: 6) Engel, H. J., Torres, C. and Page, H. L.: Major variations in anatomical origin of the coronary arteries: angiographic observations in 4, 250 patients without associated congenital heart disease. Cathet. Cardiovasc. Diag., 1: 157, 1975. – reference: 13) Choen, L. S. and Shaw, L. D.: Fatal myocardial infarction in an 11-year old boy associated with a unique coronary artery anomary. Am. J. Cardiol., 19: 420, 1967. – reference: 28) Schwarts, L., Aldrige H. E., Corol Szarga, M. B. et al.: Percutaneus transluminal angioplasty of an anomalous left circumflex coronary artery arising from the right sinus of Valsalva. Cathet. Cardiovasc. Diag., 8: 623, 1982. |
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Title | 症例 PTCR時に遭遇した右冠動脈左バルサルバ洞起始に合併した若年性心筋梗塞の1例 |
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