Alzheimer 型痴呆と混合型痴呆における問題行動と認知機能障害との関係
痴呆に伴う問題行動と認知機能障害との関係を老人保健施設に入所中の Alzheimer 型痴呆 (DAT) 患者57名と混合型痴呆 (MIX) 患者31名を対象に検討した. DATの診断はDSM-III-Rに従い, MIXの診断はDSM-III-Rと Hachinski の虚血スコアーを参考にした. 認知機能は Mini-Mental State (MMS) で, 問題行動は Baumgarten らの Dementia Behavior Disturbance (DBD) スケールで評価した. DAT群では, MMSとDBD得点は有意に相関したのに対し, MIX群では両者は相関しなかった. M...
Saved in:
| Published in | 日本老年医学会雑誌 Vol. 31; no. 11; pp. 860 - 864 |
|---|---|
| Main Authors | , , |
| Format | Journal Article |
| Language | Japanese |
| Published |
一般社団法人 日本老年医学会
01.11.1994
|
| Subjects | |
| Online Access | Get full text |
| ISSN | 0300-9173 |
| DOI | 10.3143/geriatrics.31.860 |
Cover
| Abstract | 痴呆に伴う問題行動と認知機能障害との関係を老人保健施設に入所中の Alzheimer 型痴呆 (DAT) 患者57名と混合型痴呆 (MIX) 患者31名を対象に検討した. DATの診断はDSM-III-Rに従い, MIXの診断はDSM-III-Rと Hachinski の虚血スコアーを参考にした. 認知機能は Mini-Mental State (MMS) で, 問題行動は Baumgarten らの Dementia Behavior Disturbance (DBD) スケールで評価した. DAT群では, MMSとDBD得点は有意に相関したのに対し, MIX群では両者は相関しなかった. MMSが20点以上の認知機能障害の軽度な患者に対象を限定すると, DAT, MIX群のMMS平均得点は同等であるにも拘らず, DBD得点はMIX群のほうが高値であった. 以上のことから, DAT患者では問題行動は認知機能障害の進行に並行して出現, 増加することが示唆された. しかし, そこに脳血管性病変が重なると両者の障害は並行せず, 認知機能障害の軽い時点から問題行動が目立つ傾向にあると思われた. |
|---|---|
| AbstractList | 痴呆に伴う問題行動と認知機能障害との関係を老人保健施設に入所中の Alzheimer 型痴呆 (DAT) 患者57名と混合型痴呆 (MIX) 患者31名を対象に検討した. DATの診断はDSM-III-Rに従い, MIXの診断はDSM-III-Rと Hachinski の虚血スコアーを参考にした. 認知機能は Mini-Mental State (MMS) で, 問題行動は Baumgarten らの Dementia Behavior Disturbance (DBD) スケールで評価した. DAT群では, MMSとDBD得点は有意に相関したのに対し, MIX群では両者は相関しなかった. MMSが20点以上の認知機能障害の軽度な患者に対象を限定すると, DAT, MIX群のMMS平均得点は同等であるにも拘らず, DBD得点はMIX群のほうが高値であった. 以上のことから, DAT患者では問題行動は認知機能障害の進行に並行して出現, 増加することが示唆された. しかし, そこに脳血管性病変が重なると両者の障害は並行せず, 認知機能障害の軽い時点から問題行動が目立つ傾向にあると思われた. |
| Author | 栗田, 正 栗田, 正文 磯貝, 行秀 |
| Author_xml | – sequence: 1 fullname: 磯貝, 行秀 organization: 東京慈恵会医科大学第3内科 – sequence: 1 fullname: 栗田, 正 organization: 東京慈恵会医科大学第3内科 – sequence: 1 fullname: 栗田, 正文 organization: 老人保健施設幸正の苑 |
| BookMark | eNpNkM1Kw0AAhPdQwVr7AN58gdTd7k-yx1L8g4AXvRo2cdOmpFU2vegtFURsi_ZQBRFLBcEf6EWhJ_FhYtrmLQxY1MsM8zHMYZZApnHYkACsIFjAiOC1ilSeaCrPCdJcMBjMgCzEEGoc6XgR5IPAsyE1CCeMwSzYL_knVenVpVqN79vTm_e4dxaFT5PxOL46_0deo_AiCntRqx33L5NhZzbsxO1-2py9dKeDx8nzYHb6kdzexaO3FEbhKLl--PpsLYMFV_iBzM89B_Y21nfLW5q5s7ldLplaDRmEaEWHQgoNzpBLKbUpgjpyCcXkgApRFNi1uSScUdtxsZCGwXXKqetgW2cEYV7EOWD-7NaCpqhI60h5daGOLaGanuNL6-8VxBmxMLIQmmt60W_NqQpl1QT-Bi7Rgpc |
| ContentType | Journal Article |
| Copyright | 社団法人 日本老年医学会 |
| Copyright_xml | – notice: 社団法人 日本老年医学会 |
| DOI | 10.3143/geriatrics.31.860 |
| DatabaseTitleList | |
| DeliveryMethod | fulltext_linktorsrc |
| Discipline | Medicine |
| EndPage | 864 |
| ExternalDocumentID | article_geriatrics1964_31_11_31_11_860_article_char_ja |
| GroupedDBID | ALMA_UNASSIGNED_HOLDINGS CS3 F5P JSF KQ8 OK1 RJT |
| ID | FETCH-LOGICAL-j1844-2c50508961f555b51071f4534d5aa2a3fb9e4965bcf3ae8897595fc3b76413923 |
| ISSN | 0300-9173 |
| IngestDate | Wed Sep 03 06:23:34 EDT 2025 |
| IsDoiOpenAccess | true |
| IsOpenAccess | true |
| IsPeerReviewed | false |
| IsScholarly | true |
| Issue | 11 |
| Language | Japanese |
| LinkModel | OpenURL |
| MergedId | FETCHMERGED-LOGICAL-j1844-2c50508961f555b51071f4534d5aa2a3fb9e4965bcf3ae8897595fc3b76413923 |
| OpenAccessLink | https://www.jstage.jst.go.jp/article/geriatrics1964/31/11/31_11_860/_article/-char/ja |
| PageCount | 5 |
| ParticipantIDs | jstage_primary_article_geriatrics1964_31_11_31_11_860_article_char_ja |
| PublicationCentury | 1900 |
| PublicationDate | 19941100 |
| PublicationDateYYYYMMDD | 1994-11-01 |
| PublicationDate_xml | – month: 11 year: 1994 text: 19941100 |
| PublicationDecade | 1990 |
| PublicationTitle | 日本老年医学会雑誌 |
| PublicationTitleAlternate | 日老医誌 |
| PublicationYear | 1994 |
| Publisher | 一般社団法人 日本老年医学会 |
| Publisher_xml | – name: 一般社団法人 日本老年医学会 |
| References | 4) Teni L, Larson EB, Reifler BV: Behavioral disturbance in dementia of the Alzheimer's type. J Am Geriatr Soc 1988; 36: 1-6. 13) Hachinski VC, Iliff LD, Zilhka E, DuBoulay GH, McAllister VL, Marshall J, et al: Cerebral blood flow in dementia. Arch Neurol 1975; 32: 632-637. 14) Folstein M, Folstein S, McHugh PR: Mini-Mental State: A practical method for grading the cognitive state of patients for the clinician. J Psychiatr Res 1975; 12: 189-198. 16) 溝口環, 飯島節, 江藤文夫, 石塚彰映, 折茂肇: DBDスケール (Dementia Behavior Disturbance Scale) による老年期痴呆患者の行動異常評価に関する研究. 日老医誌1993; 30: 835-840. 18) Cooper JK, Mungas D: Risk factor and behavioral differences between vascular and Alzheimer's dementias: The pathway to end-stage disease. J Geriatr Psychiatry Neurol 1993; 1: 29-33. 12) American Psychiatric Association: Diagnostic and Statistical Manual of Mental Disorders, 3rd edition-revised, American Psychiatric Association, Washington DC, 1987. 9) Kurita A, Blass JP, Nolan KA, Black RS, Thaler HT: Relationship between cognitive status and behavioral symptoms in Alzheimer's disease and mixed dementia. J Am Geriatr Soc 1993; 41: 732-736. 17) Stuss DT, Gow CA, Hetherington CR: “No longer gage”: Frontal lobe dysfunction and emotional changes. J Consult Clin Psychology 1992; 60: 349-359. 7) Cooper JK, Mungas D, Weiler PG: Relation of cognitive status and abnormal behaviors in Alzheimer's disease. J Am Geriatr Soc 1990; 38: 867-870. 8) Patterson MB, Schnell AH, Martin RJ, Mendez MF, Smyth KA, Whitehouse PJ: Assessment of behavioral and affective symptoms in Alzheimer's disease. J Geriatr Psychiatry Neurol 1990; 3: 21-30. 6) Burns A, Jacoby R, Levy R: Psychiatric phenomena in Alzheimer's disease. IV: Disorders of behaviour. Br J Psychiatry 1990; 157: 86-94. 11) Jellinger K, Danielczyk W, Fischer P, Gabriel E: Clinicopathological analysis of dementia disorders in the elderly. J Neurol Sci 1990; 95: 239-258. 15) Baumgarten M, Becker R, Gauthier S: Validity and reliability of the Dementia Behavior Disturbance scale. J Am Geriatr Soc 1990; 38: 221-226. 2) Rubin EH, Morris JC, Berg L: The progression of personality changes in senile dementia of the Alzheimer's type. J Am Geriatr Soc 1987; 35: 721-725. 10) Mölsä PK, Paljärvi L, Rinne JO, Rinne UK, Säkö E: Validity of clinical diagnosis in dementia: A prospective clinicopathological study. J Neurol Neurosurg Psychiatry 1985; 48: 1085-1090. 5) Teni L, Borson S, Kiyak HA, Yamagishi M: Behavioral disturbance, cognitive dysfunction, and functional skill. Prevalence and relationship in Alzheimer's disease. J Am Geriatr Soc 1989; 37: 109-116. 1) Steele C, Rovner B, Chase GA, Folstein M: Psychiatric symptoms and nursing home placement of patients with Alzheimer's disease. Am J Psychiatry 1990; 147: 1049-1051. 3) Merriam AE, Aronson MK, Gaston P, Wey SL, Katz I: The psychiatric symptoms of Alzheimer's disease. J Am Geriatr Soc 1988; 36: 7-12. |
| References_xml | – reference: 17) Stuss DT, Gow CA, Hetherington CR: “No longer gage”: Frontal lobe dysfunction and emotional changes. J Consult Clin Psychology 1992; 60: 349-359. – reference: 6) Burns A, Jacoby R, Levy R: Psychiatric phenomena in Alzheimer's disease. IV: Disorders of behaviour. Br J Psychiatry 1990; 157: 86-94. – reference: 11) Jellinger K, Danielczyk W, Fischer P, Gabriel E: Clinicopathological analysis of dementia disorders in the elderly. J Neurol Sci 1990; 95: 239-258. – reference: 16) 溝口環, 飯島節, 江藤文夫, 石塚彰映, 折茂肇: DBDスケール (Dementia Behavior Disturbance Scale) による老年期痴呆患者の行動異常評価に関する研究. 日老医誌1993; 30: 835-840. – reference: 8) Patterson MB, Schnell AH, Martin RJ, Mendez MF, Smyth KA, Whitehouse PJ: Assessment of behavioral and affective symptoms in Alzheimer's disease. J Geriatr Psychiatry Neurol 1990; 3: 21-30. – reference: 5) Teni L, Borson S, Kiyak HA, Yamagishi M: Behavioral disturbance, cognitive dysfunction, and functional skill. Prevalence and relationship in Alzheimer's disease. J Am Geriatr Soc 1989; 37: 109-116. – reference: 7) Cooper JK, Mungas D, Weiler PG: Relation of cognitive status and abnormal behaviors in Alzheimer's disease. J Am Geriatr Soc 1990; 38: 867-870. – reference: 1) Steele C, Rovner B, Chase GA, Folstein M: Psychiatric symptoms and nursing home placement of patients with Alzheimer's disease. Am J Psychiatry 1990; 147: 1049-1051. – reference: 4) Teni L, Larson EB, Reifler BV: Behavioral disturbance in dementia of the Alzheimer's type. J Am Geriatr Soc 1988; 36: 1-6. – reference: 18) Cooper JK, Mungas D: Risk factor and behavioral differences between vascular and Alzheimer's dementias: The pathway to end-stage disease. J Geriatr Psychiatry Neurol 1993; 1: 29-33. – reference: 2) Rubin EH, Morris JC, Berg L: The progression of personality changes in senile dementia of the Alzheimer's type. J Am Geriatr Soc 1987; 35: 721-725. – reference: 14) Folstein M, Folstein S, McHugh PR: Mini-Mental State: A practical method for grading the cognitive state of patients for the clinician. J Psychiatr Res 1975; 12: 189-198. – reference: 12) American Psychiatric Association: Diagnostic and Statistical Manual of Mental Disorders, 3rd edition-revised, American Psychiatric Association, Washington DC, 1987. – reference: 13) Hachinski VC, Iliff LD, Zilhka E, DuBoulay GH, McAllister VL, Marshall J, et al: Cerebral blood flow in dementia. Arch Neurol 1975; 32: 632-637. – reference: 3) Merriam AE, Aronson MK, Gaston P, Wey SL, Katz I: The psychiatric symptoms of Alzheimer's disease. J Am Geriatr Soc 1988; 36: 7-12. – reference: 10) Mölsä PK, Paljärvi L, Rinne JO, Rinne UK, Säkö E: Validity of clinical diagnosis in dementia: A prospective clinicopathological study. J Neurol Neurosurg Psychiatry 1985; 48: 1085-1090. – reference: 9) Kurita A, Blass JP, Nolan KA, Black RS, Thaler HT: Relationship between cognitive status and behavioral symptoms in Alzheimer's disease and mixed dementia. J Am Geriatr Soc 1993; 41: 732-736. – reference: 15) Baumgarten M, Becker R, Gauthier S: Validity and reliability of the Dementia Behavior Disturbance scale. J Am Geriatr Soc 1990; 38: 221-226. |
| SSID | ssib058494660 ssj0055462 ssib002821993 ssib005879752 ssib000994798 ssib000940319 |
| Score | 1.4226866 |
| Snippet | 痴呆に伴う問題行動と認知機能障害との関係を老人保健施設に入所中の Alzheimer 型痴呆 (DAT) 患者57名と混合型痴呆 (MIX) 患者31名を対象に検討した. DATの診断はDSM-III-Rに従い, MIXの診断はDSM-III-Rと Hachinski の虚血スコアーを参考にした. 認知機能は... |
| SourceID | jstage |
| SourceType | Publisher |
| StartPage | 860 |
| SubjectTerms | アルツハイマー型痴呆 問題行動 混合型痴呆 行動障害 認知機能障害 |
| Title | Alzheimer 型痴呆と混合型痴呆における問題行動と認知機能障害との関係 |
| URI | https://www.jstage.jst.go.jp/article/geriatrics1964/31/11/31_11_860/_article/-char/ja |
| Volume | 31 |
| hasFullText | 1 |
| inHoldings | 1 |
| isFullTextHit | |
| isPrint | |
| ispartofPNX | 日本老年医学会雑誌, 1994/11/25, Vol.31(11), pp.860-864 |
| link | http://utb.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMwrR3LahRBcAgRRA_iE9_kYJ1k4zy6Z7qPPdlZghJBSCAnl5nZGXXRKJpcctsIIiaiOURBxBBB8AG5KOQkfsy6efyFVT09u-PjEKMwDL3VVdVVXdNTVbP9sKwL3E9dlruyJmjfWea2eE04aasmEBzHsZNkMSWKE1f98Sl2eZpPDw0frMxamptNRtP5P64r2YtVEYZ2pVWyf2HZPlMEYBnti3e0MN53ZWN1e_5mdusO7QYRcZARiBCiAGQAIdMQB4QPkYfhIigBkQ9hQBdV2SDELqhCUxDKFLCWCq6mQmQOogGRBIU4YxCJssAJAWsHrWOVAlHXbTVAcZJHSSpjlfAgrBMfqUBqchVB6FXIi0KkcZDQhYhB2IDiUKEyviaeqEjBHPkoLZKwiRZ5htLoiBKGWn5VB-VrVmPUNDEPtY6FtP1vyCS18kBpYUMXZJ0ezoq-WB2AsAf4KKNNspC6yN4u8H3dordLNK2FDyZYaJnVisysUiyHkxZfa0m6Cq00ioPASJsoNJywO8kgCFd4XfzHvqq4EM-20Z0Vh8WU_s54XTOunYr3EsXRDmUgVGwv_6uP9TDCxoFxg4YRHSLxACGjfcqfti43A6M5wKXt35qeg3mnuSNhs0SjdYbNNiY7-9wg0HMurlyr5AqS0Yq7ym_Jgsq3Ale4NBl14FxEIAPej90x0KajFOwyTKPZmeYvxqKLiikPpN2l33TD8LSNyVo50VPHnpOHrUMmaRxRhQZHrKF2fNTaP2GmxRyzrvdfBCO9N4tbL7_0lh91O-83NzZ6zx9XIJ-6nSfdznJ3YbG38mxnbWl7bam3uIKY2x-fbq2-2_ywuv3w686r1731zwjsdtZ3Xrz9_m3huDXViCbHxmvm4JRa2xGM1dwU8xpbSN_JOecJut3AyRn3WIvHsRt7eSIzOiciSXMvzoTAfpI8T70k8DGmxZTvhDU8c3cmO2mNeDLJfB9jIJ96psUTh6V-zkTcSmgnyeCUFRU907xX7I7T3JvRT_8nPmesA4NxeNYanr0_l53DtGE2Oa8fpx-AEuV9 |
| linkProvider | Colorado Alliance of Research Libraries |
| openUrl | ctx_ver=Z39.88-2004&ctx_enc=info%3Aofi%2Fenc%3AUTF-8&rfr_id=info%3Asid%2Fsummon.serialssolutions.com&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=article&rft.atitle=Alzheimer+%E5%9E%8B%E7%97%B4%E5%91%86%E3%81%A8%E6%B7%B7%E5%90%88%E5%9E%8B%E7%97%B4%E5%91%86%E3%81%AB%E3%81%8A%E3%81%91%E3%82%8B%E5%95%8F%E9%A1%8C%E8%A1%8C%E5%8B%95%E3%81%A8%E8%AA%8D%E7%9F%A5%E6%A9%9F%E8%83%BD%E9%9A%9C%E5%AE%B3%E3%81%A8%E3%81%AE%E9%96%A2%E4%BF%82&rft.jtitle=%E6%97%A5%E6%9C%AC%E8%80%81%E5%B9%B4%E5%8C%BB%E5%AD%A6%E4%BC%9A%E9%9B%91%E8%AA%8C&rft.au=%E7%A3%AF%E8%B2%9D%2C+%E8%A1%8C%E7%A7%80&rft.au=%E6%A0%97%E7%94%B0%2C+%E6%AD%A3&rft.au=%E6%A0%97%E7%94%B0%2C+%E6%AD%A3%E6%96%87&rft.date=1994-11-01&rft.pub=%E4%B8%80%E8%88%AC%E7%A4%BE%E5%9B%A3%E6%B3%95%E4%BA%BA+%E6%97%A5%E6%9C%AC%E8%80%81%E5%B9%B4%E5%8C%BB%E5%AD%A6%E4%BC%9A&rft.issn=0300-9173&rft.volume=31&rft.issue=11&rft.spage=860&rft.epage=864&rft_id=info:doi/10.3143%2Fgeriatrics.31.860&rft.externalDocID=article_geriatrics1964_31_11_31_11_860_article_char_ja |
| thumbnail_l | http://covers-cdn.summon.serialssolutions.com/index.aspx?isbn=/lc.gif&issn=0300-9173&client=summon |
| thumbnail_m | http://covers-cdn.summon.serialssolutions.com/index.aspx?isbn=/mc.gif&issn=0300-9173&client=summon |
| thumbnail_s | http://covers-cdn.summon.serialssolutions.com/index.aspx?isbn=/sc.gif&issn=0300-9173&client=summon |