Successful emergency operation for subdural hematoma and acute epidural hematoma in a patient with acute promyelocytic leukemia

A 22-year-old woman was admitted with purpura. Acute promyelocytic leukemia (APL) with disseminated intravascular coagulation (DIC) was diagnosed. On the 17th day after treatment with all-trans retinoic acid (ATRA), left subdural hematoma developed. Although coagulation abnormalities were still obse...

Full description

Saved in:
Bibliographic Details
Published inRinshō ketsueki Vol. 40; no. 7; p. 606
Main Authors Yamaji, S, Kanamori, H, Tanaka, M, Mishima, A, Koharazawa, H, Fujita, H, Fujisawa, S, Murata, T, Matsuzaki, M, Mohri, H, Ishigatsubo, Y
Format Journal Article
LanguageJapanese
Published Japan 01.07.1999
Subjects
Acute Disease
Adult
Emergencies
Female
Hematoma, Epidural, Cranial - surgery
Hematoma, Subdural - surgery
Humans
Leukemia, Promyelocytic, Acute - complications
Online AccessGet more information

Cover

More Information
Summary:A 22-year-old woman was admitted with purpura. Acute promyelocytic leukemia (APL) with disseminated intravascular coagulation (DIC) was diagnosed. On the 17th day after treatment with all-trans retinoic acid (ATRA), left subdural hematoma developed. Although coagulation abnormalities were still observed, emergency surgery was performed. Acute epidural hematoma was confirmed by computed tomographic scan after the operation. A second operation for drainage was successful. Post-operative intracranial hematoma may be caused by rapid decompression induced by surgery, but DIC could also be involved. This case underscored the need for careful consideration of the indications for surgical treatment of such DIC patients, with close follow-up monitoring for the postoperative development of neurological symptoms.
ISSN:0485-1439
DOI:10.11406/rinketsu.40.606