Risk factors for coronary artery disease in Japanese patients with chronic renal failure

• Published in: Nihon Jinzo Gakkai shi Vol. 35; no. 6; pp. 751 - 756
• Main Authors: UI, KATSUTO, IMAMURA, YOSHIHIKO, INISHI, YOJI, YAMAGUCHI, TETSU, NAKAMURA, RYOICHI, JYOKI, NOBUHIKO, HASE, HIROKI, YASUDA, CHIKAKO, ISHIKAWA, HIROYASU, YABUKI, SO
• Format: Journal Article
• Language: Japanese
• Published: Japan Japanese Society of Nephrology 01.06.1993
• Subjects: Adult; Aged; Aged, 80 and over; Coronary Disease - epidemiology; Coronary Disease - etiology; coronary risk factor, coronary artery disease, chronic renal failure, lipoprotein (a); Diabetic Nephropathies - complications; Female; Humans; Japan - epidemiology; Kidney Failure, Chronic - blood; Kidney Failure, Chronic - complications; Lipoproteins - blood; Male; Middle Aged; Regression Analysis; Risk Factors; Smoking; Japan
• ISSN: 0385-2385; 1884-0728
• DOI: 10.14842/jpnjnephrol1959.35.751

We examined the records of 101 Japanese patients with chronic renal failure (CRF) to determine the influence of established risk factors on the incidence of coronary artery disease (CAD). CAD was found in 25 patients (myocardial infarction in 18, significant coronary artery stenosis by coronary angiogram in 16). In patients with CAD, there were significantly more male (80% vs 58%, p<0.05), more smokers (80% vs 41 %, p<0. 0005), more diabetics (68% vs 32%, p<0.005) and more hypertensives (92% vs 76%, p<0.05). However, lipoprotein (a), high-density lipoprotein cholesterol, low-density lipoprotein cholesterol, or triglycerides were not significantly defferent between CAD group and control group. When significant risk factors were entered into a stepwise logistic regression analysis, we found a history of smoking (p=0.0025) and the presence of diabetes (p=0.0141) to be independent risk factors for the presence of CAD in Japanese patients with CRF.