Therapeutic effectiveness of cefluprenam on infections associated with hematologic disorders

• Published in: Japanese Journal of Chemotherapy Vol. 43; no. Supplement4; pp. 253 - 255
• Main Authors: Isikawa, Takahisa, Maekawa, Isao, Fukuhara, Takashi, Miyake, Takayoshi
• Format: Journal Article
• Language: Japanese
• Published: Japanese Society of Chemotherapy 1995; 公益社団法人 日本化学療法学会
• Subjects: cefluprenam; 敗血症
• ISSN: 1340-7007; 1884-5886
• DOI: 10.11250/chemotherapy1995.43.Supplement4_253

The clinical efficacy and safety of cefluprenam (CFLP), a newly developed cephalosporin antibiotic, on infections associated with hematologic disorders were investigated in 1 patient with sepsis, 4 with sepsis suspected, 3 with acute pharyngitis, 1 with acute bronchitis and 1 with bronchopneumonia. CFLP was administered by intravenous drip infusion at a dose of 1.0 or 2.0 g twice a day for 6-19 days. Clinical responses were excellent in 4, good in 1, fair in 1 and poor in 2 cases. Skin rash was observed in 1 patient. Abnormal laboratory findings were observed in 2 patients.