CLINICAL ANALLYSIS OF HYPOPHARYNGEAL MALIGNANT TUMORS

• Published in: JIBI INKOKA TEMBO Vol. 56; no. Supplement1; pp. s92 - s96
• Main Authors: Nishimura, Bungo, Yoshimura, Tomonori, Ashizawa, Kei, Nakayama, Masahiro, Hirose, Yuki, Hoshino, Tomofumi, Uemaetomari, Isao, Tobita, Tadamichi, Tabuchi, Keiji, Ohkubo, Hideki, Wada, Tetsuro, Hara, Akira
• Format: Journal Article
• Language: Japanese
• Published: Society of Oto-rhino-laryngology Tokyo 05.03.2013; 耳鼻咽喉科展望会
• Subjects: chemoradiotherapy; hypopharyngeal cancer; surgical operation; survival rate; 下咽頭癌; 手術療法; 放射線化学療法; 生存率
• ISSN: 0386-9687; 1883-6429
• DOI: 10.11453/orltokyo.56.s92

A total of 84 patients with hypopharyngeal malignant tumors were treated at the University of Tsukuba Hospital between 2002 and 2011. In all patients, the tumors were histopathologically diagnosed as squamous cell carcinoma. The mean age was 66.0 years and the male-female ratio was 9.6: 1. The primary lesions were in the piriform sinus in 83.3%, the posterior wall in 9.5% and the postcricoid area in 7.2% of the cases. The majority (87.0%) of the patients had advanced cancer (stage III or IV), and the main treatment modality used was concurrent chemoradiotherapy. Total pharyngolaryngectomy was performed in 19 cases. The disease-specific 5-year survival rate was 53.8%. The 5-year survival rate in the group that was treated by total pharyngo-laryngectomy was 76.5%, much better than that in the entire subject population of hypopharyngeal cancer. Therefore, surgery appears to be important to improve the prognosis of this disease.