Elastic Fibers in Morphea and PSS Examination by image analyzer and electron microscopy

We examined elastic fibers in the skin of patients with scleroderma using a computarized digital image analyzer and an electron microscopy. By the image analyzer the fraction area, maximum length and breadth of the elastic fibers in three age groups (children, young adults and old adults) were analy...

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Published inSkin research Vol. 30; no. 6; pp. 717 - 721
Main Authors TSUJI, Takuo, KATO, Haruhisa, SAWABE, Motokazu, YORIFUJI, Tokiko, HAMADA, Toshio
Format Journal Article
LanguageEnglish
Published Meeting of Osaka Dermatological Association 1988
Subjects
elastic fibers
image analyzer
mor phea
PSS
ultrastructure
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Summary:We examined elastic fibers in the skin of patients with scleroderma using a computarized digital image analyzer and an electron microscopy. By the image analyzer the fraction area, maximum length and breadth of the elastic fibers in three age groups (children, young adults and old adults) were analyzed. These were all significantly increased in children's group of morphea when compared with an agematched control group. The fraction area was prone to decrease in both the young adults' and the old adults' groups of PSS. There were no significant changes in the ultrastructure of elastic fibers in both morphea and PSS except for one patient with PSS.
ISSN:0018-1390
1884-541X
DOI:10.11340/skinresearch1959.30.717