A case of cirrhosis with hepatitis C virus infection developing hepatocellular carcinoma 20 years after achieving sustained virological response to interferon therapy

An 86-year-old male was diagnosed with liver cirrhosis and hepatitis C virus (HCV) infection, and he was treated with interferon (IFN) therapy 20 years ago. He achieved a sustained virological response (SVR) and was followed up with blood tests and ultrasonography twice a year. Twenty years later, a...

Full description

Saved in:
Bibliographic Details
Published inKanzo Vol. 57; no. 1; pp. 27 - 33
Main Authors Okabe, Junya, Fukuda, Kazuto, Iwamoto, Takayuki, Yamagata, Yosuke, Tani, Mizuki, Yasuoka, Hidetaka, Yagi, Mai, Onishi, Atsunori, Kogita, Sachiyo, Sawai, Yoshiyuki, Igura, Takumi, Yamaguchi, Noritaka, Matsumoto, Yasushi, Nakahara, Masanori, Ohashi, Hiroshi, Marukawa, Taro, Maeda, Yuichi, Shinomura, Yasuhisa, Imai, Yasuharu
Format Journal Article
LanguageJapanese
Published The Japan Society of Hepatology 01.02.2016
Subjects
hepatocellular carcinoma
interferon
long time
sustained virological response
type C hepatic cirrhosis
Online AccessGet full text

Cover

More Information
Summary:An 86-year-old male was diagnosed with liver cirrhosis and hepatitis C virus (HCV) infection, and he was treated with interferon (IFN) therapy 20 years ago. He achieved a sustained virological response (SVR) and was followed up with blood tests and ultrasonography twice a year. Twenty years later, a high-echoic nodule with 15 mm diameter was detected by ultrasonography and diagnosed as a hepatocellular carcinoma by magnetic resonance imaging and hepatic angiography. The patient was treated with transcatheter arterial chemoembolization followed by radiofrequency ablation. Long-term follow-up may be needed for patients with HCV even after the achievement of SVR to IFN therapy.
ISSN:0451-4203
1881-3593
DOI:10.2957/kanzo.57.27