A CASE REPORT OF A MULTICENTRIC, MINUTE EARLY ESOPHAGEAL CANCER

• Published in: Journal of The Showa Medical Association Vol. 51; no. 5; pp. 577 - 582
• Main Authors: NAKANO, Hiroshi, NAMATAME, Kimio, SASAKI, Eiichi, MIDORIKAWA, Takemasa, OHKUBO, Masahiko, MAKUUCHI, Mikio, IWAI, Hiroko, IKEDA, Tadaaki, NAKAYOSHI, Akio, SAGAWA, Fumiake
• Format: Journal Article
• Language: English; Japanese
• Published: The Showa University Society 1991
• Subjects: minute early esophageal cancer; multicentcic esophageal cancer
• ISSN: 0037-4342; 2185-0976
• DOI: 10.14930/jsma1939.51.577

Many cases of early esophageal cancer in which the depth of invasion is limited to the submucosal layer with no lymph-node metastasis have recently been reported in Japan, although minute early esophageal cancer with diameter less than 1.0cm is considered to be uncommon. W e report a case of minute early esophageal cancer with a size of 0.5×0.4cm as a formalin-fixed specimen. This small cancer was also found to be multicentric. The lesion was located endoscopically 35cm from the incisors, and was seen as a small red depressed area. Lugol staining revealed two small unstained areas. A total thoracic esophageal resection was performed. We prepared serial sections of these lesions and observed them microscopically. The two small lesions that were not stained with Lugol's solution were found to be independent multicentric cancers. The histological type was well-differentiated squamous cell carcinoma with cancer pearls, and the depth of invasion was limited to the lamina muscularis mucosae of the esophageal wall.