Circulating blood volume measurement using pulse dye-densitometory in surgical patients

• Published in: Japanese Journal of Reanimatology Vol. 18; no. 2; pp. 122 - 124
• Main Authors: Nakakimura, Kazuhiko, Kunihiro, Mitsuru, Ishida, Kazuyoshi, Kawata, Ryuichi, Miyazaki, Takanao, Sakabe, Takefumi
• Format: Journal Article
• Language: Japanese
• Published: The Japanese Society of Reanimatology 1999; 日本蘇生学会
• Subjects: Circulating blood volume; Indocyanine green; Pulse dye-densitometory; インドシアニングリーン; 循環血液量; 脈波分光法; 色素希釈法
• ISSN: 0288-4348; 1884-748X
• DOI: 10.11414/jjreanimatology1983.18.122

We measured circulating blood volume (CBV) in 42 elective surgical patients (24 male and 18 female, 19-74 years old) after induction of anesthesia (before the start of surgery) using DDG-2001 (Nihon Kohden Corp.), which enabled us to monitor arterial concentration of indocyanine green and provided CBV calculation. CBV and CBV per body weight were 4.7±1.1l and 81±18 ml/kg (Mean±SD), respectively. CBV had a significant but weak correlation with body weight and body surface area (r=0.494, P=0.0009 and r=0.557, P=0.0001, respectively), with the maximum value of 6.5l observed in obese patients whose weight exceeded 80 kg. There were no significant differences in CBV per body weight (ml/kg) between sexes (81±17 in male, 88±32 in female), and among ages (83±30 in 65 y>, 85±19 in 65 y≤) . The instrument used in the present study facilitated simple and minimally invasive bed-side monitoring of CBV and has been shown to provide reliable CBV values comparable to the values obtained with the conventional radioisotope method. Measurement of CBV is useful not only for circulatory management but also for determination of appropriate drugs doses.