A CASE OF HEMORRHAGIC COLITIS ASSOCIATED WITH FULFENAMIC ACID ALUMINIUM

A 74-year-old female patient had taken 250mg of fulfenamic acid aluminium (FFAA) three times a day for gonarhrisis and two weeks later, abdominal pain, diarrhea bloody stool were obserbed. And she was admitted to our hospital. A barium enema examination showed many diverticles in the descending colo...

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Bibliographic Details
Published inJapanese Journal of National Medical Services Vol. 47; no. 12; pp. 999 - 1003
Main Authors KAWAGUCHI, Misao, SAOSHIRO, Takeo, HIRATSUKA, Atsushi, HONDA, Sanpei, NAKAYAMA, Hideji
Format Journal Article
LanguageJapanese
Published Japanese Society of National Medical Services 1993
Subjects
fulfenamic acid aluminium
hemorrhagic colitis
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Summary:A 74-year-old female patient had taken 250mg of fulfenamic acid aluminium (FFAA) three times a day for gonarhrisis and two weeks later, abdominal pain, diarrhea bloody stool were obserbed. And she was admitted to our hospital. A barium enema examination showed many diverticles in the descending colon. On the colonoscopic examination performed at the time of admission, edema and reddish mucosa with hemorrhage in the descending colon were noticed. Stool cultures were negative for bacterial and fungal pathogens. FFAA was discontinued and her symptoms disappeared. Lymphocyte stimulation test for FFAA was negative. Three years before, she had had the same symptoms, when she had taken 250mg of FFAA three times a day for 3 months. Discontinuation of taking the FFAA resulted in the disappearance of the symptoms. A tentative diagnosis of hemorrhagic colitis associated with FFAA was made. So far, hemorrhagic colitis associated with FFAA has been reported in three cases including the present one until the year 1990. We discussed our case, compared with 15 cases of hemorrhagic colitis associated with mefenamic acid.
ISSN:0021-1699
1884-8729
DOI:10.11261/iryo1946.47.999