FIVE CASES OF RENAL CANCER WITH BONE METASTASIS AS AN INITIAL SYMPTOM

• Published in: Japanese Journal of National Medical Services Vol. 48; no. 9; pp. 753 - 756
• Main Authors: AOTA, Yasuhiro, OKAMOTO, Noriko, MORIKAWA, Shiro, YOSHIDA, Kazuhiko
• Format: Journal Article
• Language: Japanese
• Published: Japanese Society of National Medical Services 1994
• Subjects: bone metastasis; initial symptom; renal cell carcinoma
• ISSN: 0021-1699; 1884-8729
• DOI: 10.11261/iryo1946.48.753

With the development of ultrasound and other diagnostic techniques, chance discovery of kidney cancer has increased but many are cases in which the cancer has metastasized. We report 5 recently encountered cases of kidney cancer diagnosed from bone metastase with a brief discussion. The patients were all males ranging in age from 44 to 70 years. Metastatic focis were located in the right stibia, 6th and 7th thoracic vertebrae, right pelvis, 2nd lumbar vertebra, and multiple metastases originating in the right pelvis, respectively. Initially, the pain presented in a locus corresponding to the focus. Two cases with metastasis to the spine had paralysis of the lower half of their body. Three cases underwent nephrectomy and one underwent subtotal cordotomy. Two cases were irradiated for the metastatic foci. As to the treatment, interferon was used in 4 cases, MVB in 2 and UFT in 3. Morphine hydrochloride was used in 3 cases for pain. Four patients died over 2 to 38 months (mean: 5.7 months) following the initiation of the treatment. Only one case survived the cancer for 18 months. Chemotherapy and irradiation were considered effective for alleviation of pain.