Immunoadsorbent: A Study on the Selective Removal of Immune Complexes in SLE

The specific adsorbents have been sought in an attempt to utilize them for removal of autoantigens, autoantibodies and immune complexes in SLE. The anion exchangers were broadly investigated for treatment in patients plasma in vitro. The following results were obtained; (1) The hydrophiric anion exc...

Full description

Saved in:
Bibliographic Details
Published inJinko Zoki Vol. 11; no. 2; pp. 465 - 467
Main Authors FURUTA, T., YAMAWAKI, N., INAGAKI, K., KATOH, M., NIWA, T., MAEDA, K.
Format Journal Article
LanguageJapanese
Published JAPANESE SOCIETY FOR ARTIFICIAL ORGANS 1982
Subjects
Immune complexes
Immune diseases
Immuno adsorbent
Lupus erythematosus
Online AccessGet full text

Cover

More Information
Summary:The specific adsorbents have been sought in an attempt to utilize them for removal of autoantigens, autoantibodies and immune complexes in SLE. The anion exchangers were broadly investigated for treatment in patients plasma in vitro. The following results were obtained; (1) The hydrophiric anion exchangers had large capacities of adsorption of DNA. (2) The immobilized DNA binded large quantities of anti-DNA antibodies, anti-nuclear antibodies, futhermore, immune complexes. (3) The anion exchangers, pretreated with heparin, adsorped only partial immune complexes.
ISSN:0300-0818
1883-6097
DOI:10.11392/jsao1972.11.465