A CASE OF URINARY TUBERCULOSIS WITH MONOCLONAL IMMUNOGLOBULINEMIA (IgG-κ)

• Published in: Japanese Journal of National Medical Services Vol. 45; no. 3; pp. 282 - 285
• Main Authors: NISHINO, Satoshi, HAYASHI, Takao, ARAI, Tadashi, WADA, Shizu, MATSUSHITA, Shogen
• Format: Journal Article
• Language: Japanese
• Published: Japanese Society of National Medical Services 1991
• Subjects: benign monoclonal immunoglobulinemia; urinary tuberculosis
• ISSN: 0021-1699; 1884-8729
• DOI: 10.11261/iryo1946.45.282

This paper presents a case of urinary tuberculosis with monoclonal immunoglobulinemia (IgG-κ). An 85-year-old woman was admitted because of a low fever and general malaise. Tubercle bacilli were isolated from the urinary sediment. Pyelography revealed a vermiculation of the left renal calyx. This case was diagnosed as Lattimer's type II. The IgG level was increased to 2895mg/dl, and monoclonal κ type IgG was detected. Other serum immunoglobulins were not inhibited. The bone marrow plasmocyte count was normal (2.4%). No osseous abnormality was found. Under the diagnosis of urinary tuberculosis associated with monoclonal immunoglobulinemia (IgG-K), chemotherapy was begun. Urinary tubercle bacilli disappeared after two months of chemotherapy. Monoclonal immunoglobulin also disappeared. These suggested the possibility that monoclonal immunoglobulinemia in this patient was induced by some kind of immune response to tubercle bacilli.