THE INFLUENCE OF AGE AND GENDER ON SERUM SOLUBLE INTERLEUKIN-2 RECEPTOR (sIL-2R) AND INTERCELLULAR ADHESION MOLECULE-1 (sICAM-1) LEVELS

We examed soluble interleukin-2 receptor (sIL-2R) and soluble intercellular adhesion molecule-1 (sICAM-1) in venous blood from healthy subjects, sIL-2R and sICAM-1 are correlated with age (r=0.207, n=174, p=0.0064 and r=0.248, n=126, p=0.0065, respectively). Both factors had significantly higher lev...

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Bibliographic Details
Published inJapanese Journal of National Medical Services Vol. 54; no. 4; pp. 167 - 171
Main Authors KATAYAMA, Shouichi, IHARA, Akihiro
Format Journal Article
LanguageJapanese
Published Japanese Society of National Medical Services 2000
一般社団法人 国立医療学会
Subjects
aging
gender
sICAM-1
sIL-2R
加齢
可溶性ICAM-1
可溶性インターロイキン2受容体
性差
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ISSN0021-1699
1884-8729
DOI10.11261/iryo1946.54.167

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Summary:We examed soluble interleukin-2 receptor (sIL-2R) and soluble intercellular adhesion molecule-1 (sICAM-1) in venous blood from healthy subjects, sIL-2R and sICAM-1 are correlated with age (r=0.207, n=174, p=0.0064 and r=0.248, n=126, p=0.0065, respectively). Both factors had significantly higher levels in males than in females (p<0.007). There was statistically significant correlation between sIL-2R and sICAM-1. Changes in serum sIL-2R and sICAM-1 levels with aging and increased levels in men may be related to the developement of atherosclerosis.
ISSN:0021-1699
1884-8729
DOI:10.11261/iryo1946.54.167