CLINICAL STUDY OF LONG-TERM USE OF ART IFICIAL PANCREAS

• Published in: Jinko Zoki Vol. 19; no. 2; pp. 901 - 904
• Main Authors: ISHIHARA, Tohru, HATAGUCHI, Yoshikura, HOSHINO, Masami
• Format: Journal Article
• Language: Japanese
• Published: JAPANESE SOCIETY FOR ARTIFICIAL ORGANS 1990; 一般社団法人 日本人工臓器学会
• Subjects: Artificial Pancreas; Diabetes; Glucose Tolerance; IVH; Pseudodiabetes
• ISSN: 0300-0818; 1883-6097
• DOI: 10.11392/jsao1972.19.901

Problems and usefulness of relatively long-term use of more than one week of the artificial pancreas(a total of 200 days) was studied. The reliability of blood glucose measurement was most frequently impaired by the obstructi on of the blood sampling circuit with blood clots and the deterioration of the enzume membra ne by blood constituents. Catheter sepsis was found only two times among 15 times. With the use of artificial pancreas, the blood glucose(average of mean daily glucose level for each patient) was 180mg/dl and considered ideal. The maximal difference in daily blood glucose and the difference between the mean blood glucose and the goal set by the artificial pancreas were calculated. Most days were evaluated to be excellent or fair, but 13% of the days was poor when severe infection was existing. The insulin/energy ratio, which indicate the degree of glucose intolerance exceeded 50mu/kcal/day for more than 38% of the days, in which condi tion more than 50 units of insulin was necessary when hyperalimentation was performed. In conclusion, the artificial pancreas was useful not only in controlling blood glucose but also to evaluating the degree of glucose intolerance for long-term nutritional care.