INICALSTUDIESOFCEFOTAXIME INTHEFIELDOFSURGERY

Cefotaxime (HR 756, CTX) was used in the treatment of 14 patients with various surgical diseases, comprised of 10 cases of superficial soft tissue infections and 4 cases of perforative peritonitis. The rate of effectiveness was 80% in superficial soft tissue infections and 50% in perforative periton...

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Published inCHEMOTHERAPY Vol. 28; no. Supplement1; pp. 623 - 625
Main Authors TAKENAKA, NOBUO, KATO, SHIGETSUGU, TANAKA, TOYOHARU, NOUGA, KATSUHIKO, MIURA, SEIJI, SHIMAZU, HIROSHI
Format Journal Article
LanguageJapanese
Published Japanese Society of Chemotherapy 25.06.1980
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ISSN0009-3165
1884-5894
DOI10.11250/chemotherapy1953.28.Supplement1_623

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Summary:Cefotaxime (HR 756, CTX) was used in the treatment of 14 patients with various surgical diseases, comprised of 10 cases of superficial soft tissue infections and 4 cases of perforative peritonitis. The rate of effectiveness was 80% in superficial soft tissue infections and 50% in perforative peritonitis. The overall rate of effectiveness was therefore 71. 4%. Bacteriologically, among the 10 cases of superficial soft tissue infections, 2 strains of Peptococcus, and 1 strain each of S. epidermidis, Corynebacterium, Acinetobacter and Bacteroides were detected in 5 cases. All identified strains were eradicated after treatment. However, in the two ineffective cases of perforative peritonitis, E. coli was detected and persisted during treatment. Skin rash occurred as a side effect in 1 case and symptoms disappeared immediately upon withdrawal of the drug.
ISSN:0009-3165
1884-5894
DOI:10.11250/chemotherapy1953.28.Supplement1_623