Diffuse Infiltrative Carcinoma of the Sigmoid Colon: Report of a Case

• Published in: Japanese Journal of National Medical Services Vol. 43; no. 1; pp. 88 - 91
• Main Authors: AKIYAMA, Noriyoshi, TSUKAMOTO, Hidehito, MINOURA, Hirohiko, OHMIYA, Haruo, ASAO, Takeshi, OSAKABE, Toji, YASOKAWA, Yohei, KATO, Yasuyuki
• Format: Journal Article
• Language: Japanese
• Published: Japanese Society of National Medical Services 1989; 一般社団法人 国立医療学会
• ISSN: 0021-1699; 1884-8729
• DOI: 10.11261/iryo1946.43.88

Diffuse infiltrative carcinoma of the colon is rare and it has several problems in its diagnosis, growth, extention, and prognosis. The majority of this disease is metastasis from the carcinoma of stomach, breast and prostate, and the cases in which the colon is primary is especially rare. This is a case report of the diffuse infiltrative carcinoma of the sigmoid colon. Forty-three-year-old man was admitted because of abdominal pain, abdominal distension, tenesmus and bloody stool for about 1.5 months. A stenotic area as long as 16 cm between descending and sigmoid colon was seen and diffuse infiltrative carcinoma of the sigmoid colon was suspected by barium enema. Endo scopic study revealed the stricture of sigmoid colon at about 50 cm from anal verge. The findings of cancer was not demonstrated in the biopsy specimen taken from the anal side of the stricture. A tentative diagnosis of carcinoma of the colon was made and a part of the descending and sigmoid colon was resected. Histologically, there was a diffuse cancerous invasion with a predominant pattern of poorly differentiated adenocarcinoma accompanied with remarkable invasion to the lymphatic vessels through the entire wall below the submucosal layer.