Kinetic analysis of Beta-2-microglobulin behavior for hemodialysis patients

The objective of the present study is to clarify beta-2-microglobulin (B2-m) behavior at intra- and interdialysis periods by kinetic modelling. Pools of B2-m are composed of intracellular, interstitial and plasma spaces. Values for generation rate of B2-m for patients on long-term hemodialysis are l...

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Bibliographic Details
Published inJinko Zoki Vol. 17; no. 1; pp. 42 - 45
Main Authors TAKAGI, T., SAITO, A., OGAWA, H., SAKAI, K., HIDAI, H., TAKESAWA, S.
Format Journal Article
LanguageJapanese
Published JAPANESE SOCIETY FOR ARTIFICIAL ORGANS 1988
一般社団法人 日本人工臓器学会
Subjects
beta-2-microglobulin
generation rate
kinetic modelling
patients on long-term hemodialysis
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ISSN0300-0818
1883-6097
DOI10.11392/jsao1972.17.42

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Summary:The objective of the present study is to clarify beta-2-microglobulin (B2-m) behavior at intra- and interdialysis periods by kinetic modelling. Pools of B2-m are composed of intracellular, interstitial and plasma spaces. Values for generation rate of B2-m for patients on long-term hemodialysis are less than 100mg/day, which are lower than those of healthy subjects. Cell membrane clearance data indicate that B2-m is released easily from cell membrane surface.
ISSN:0300-0818
1883-6097
DOI:10.11392/jsao1972.17.42