A Case of Corneal Dermoid in a Crl:CD(SD) Rat
A white and round raised focus (about 2 mm in diameter) with a few hairs was macroscopically observed in the cornea of the right eye from a male among Crl:CD(SD) rats which were purchased for a toxicity study at 5 weeks of age. During one year after the discovery, there were no changes in other corn...
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Published in | Animal Eye Research Vol. 29; pp. 25 - 28 |
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Main Authors | , , , , , |
Format | Journal Article |
Language | Japanese |
Published |
Japanese Society of Comparative and Veterinary Ophthalmology
28.12.2010
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Subjects | |
Online Access | Get full text |
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Summary: | A white and round raised focus (about 2 mm in diameter) with a few hairs was macroscopically observed in the cornea of the right eye from a male among Crl:CD(SD) rats which were purchased for a toxicity study at 5 weeks of age. During one year after the discovery, there were no changes in other corneal regions, anterior portion, optic media or fundus oculi except that the raised focus increased in roundness to form a hemispheric shape and lost it's hairs. Histopathological examination conducted at 59 weeks of age revealed normal skin structure consisting of epidermis, dermis with cutaneous appendages (hair follicles, hair roots and sebaceous glands) and subcutaneous adipose tissue. From these findings, the lesion was diagnosed as a corneal dermoid. |
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ISSN: | 0286-7486 2185-8446 |
DOI: | 10.11254/jscvo.29.25 |