Pattern of renal diseases among adults in Saudi Arabia: a clinicopathologic study

In order to delineate the pattern of renal diseases among the adult population in Saudi Arabia, a retrospective study of 166 kidney biopsies performed between 1989 and 1997 at Asir Central Hospital, Abha, Southern Saudi Arabia was conducted. Primary glomerular disease accounted for 66.8% of all case...

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Bibliographic Details
Published inEthnicity & disease Vol. 9; no. 3; p. 463
Main Author Al-Homrany, M A
Format Journal Article
LanguageEnglish
Published United States 1999
Subjects
Adolescent
Adult
Aged
Aged, 80 and over
Child, Preschool
Female
Glomerulonephritis, IGA - ethnology
Glomerulonephritis, Membranoproliferative - ethnology
Humans
Incidence
Kidney Diseases - ethnology
Kidney Diseases - microbiology
Male
Middle Aged
Retrospective Studies
Saudi Arabia - epidemiology
Schistosomiasis - complications
Saudi Arabia
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Summary:In order to delineate the pattern of renal diseases among the adult population in Saudi Arabia, a retrospective study of 166 kidney biopsies performed between 1989 and 1997 at Asir Central Hospital, Abha, Southern Saudi Arabia was conducted. Primary glomerular disease accounted for 66.8% of all cases. Mesangiocapillary glomerulonephritis (MCGN) was found to be the most common histological lesion accounting for 25.9% of all cases and 38.7% of the primary nephritis. This was followed by immunoglobulin A nephropathy (IgA) (18.9%), and focal segmental glomerulosclerosis (17.1%), minimal change disease (9.9%), membranous glomerulonephritis (9.0%) and mesangioproliferative glomerulonephritis (4.5%). Lupus nephritis was the leading cause of the secondary glomerulonephritis (61.5%). Clinical evidence of schistosomiasis was seen in 4.2% of all the cases and in 11.6% of the mesangiocapillary cases. Schistosomal infection may play a role in the pathogenesis of glomerulonephritis in the Saudi population, and further studies are needed to confirm such an association.
ISSN:1049-510X