A Case of B-cell Lymphoma Complicated with Uric Acid Nephropathy and Methotrexate Nephropathy

We reported a case of B-cell lymphoma in a 12-year-old boy who was admitted to our hospital because of ascites. The treatment with vincristine and cyclophosphamide led to the complication of uric acid nephropathy, which was relieved for 4 days. Again he suffered renal dysfunction on the intensive ch...

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Published inThe Japanese Journal of Pediatric Hematology Vol. 6; no. 1; pp. 71 - 75
Main Authors SAKATA, Mariko, NAKAGAWA, Kimiko, SAKO, Masahiro, FUJINAMI, Akira, KONISHI, Shouzaburou, TAKUBO, Yoshiyuki
Format Journal Article
LanguageJapanese
Published THE JAPANESE SOCIETY OF PEDIATRIC HEMATOLOGY/ONCOLOGY 1992
特定非営利活動法人　日本小児血液・がん学会
Subjects
B細胞悪性リンパ腫
MTX腎症
尿酸腎症
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ISSN0913-8706
1884-4723
DOI10.11412/jjph1987.6.71

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Summary:We reported a case of B-cell lymphoma in a 12-year-old boy who was admitted to our hospital because of ascites. The treatment with vincristine and cyclophosphamide led to the complication of uric acid nephropathy, which was relieved for 4 days. Again he suffered renal dysfunction on the intensive chemotherapy with high dose methotrexate (MTX). This complication was considered to be due to high dose MTX. The renal function recovered completely and he has maintained complete remission for 2 years and 7 months after the onset. In case of massive ascites, we must consider the complication of uric acid nephropathy.
ISSN:0913-8706
1884-4723
DOI:10.11412/jjph1987.6.71