SENESCENCE GENE OF HUMAN FIBROBLAST CELLS

• Published in: TISSUE CULTURE RESEARCH COMMUNICATIONS Vol. 11; no. 1; pp. 43 - 48
• Main Authors: Hara, Eiji, Yamaguchi, Tomoko, Nakada, Susumu, Ide, Toshinori, Ode, Kinichiro
• Format: Journal Article
• Language: Japanese
• Published: The Japanese Tissue Culture Association 1992

Since Dr. Hayflick demonstrated that mammalian cell has a finite replicative life span in 1961, this phenomenon has been termed cellular senescence and various experiments had been carried out to elucidate the mechanisms of senescence. Recent studies using molecular biological techniques have sugges...