CLINICAL STUDIES ON CEFUZONAM IN THE FIELD OF OBSTETRICS AND GYNECOLOGY

Cefuzonam (CZON, L-105), a cephem type antibiotic, was clinically studied in the field of obstetrics and gynecology. The results are summarized as follows: CZON 1-2 g was administered by injection twice daily to 11 cases of infections (4 of endometritis, 2 of pyometra, 3 of adnexitis and peritonitis...

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Published inJapanese journal of antibiotics Vol. 40; no. 9; pp. 1617 - 1623
Main Authors SOUMA, AKIRA, YAMASHITA, KOHKI, ISHIKAWA, MUTSUO, YOROZU, YUTAKA, ASAKAWA, TAKEHITO, SHIMIZU, TETSUYA, HAGA, HIROMITSU, SAITOH, SATOSHI, SAITOH, TOYOKAZU, HASEGAWA, TENSYU, TORII, YUTAKA, SHIBATA, SHIGEO, MURE, KAZUHIDE, SATOH, TAKASHI
Format Journal Article
LanguageJapanese
Published Japan Japan Antibiotics Research Association 01.09.1987
Subjects
Adult
Aged
Bacterial Infections - drug therapy
Ceftizoxime - analogs & derivatives
Cephalosporins - adverse effects
Cephalosporins - therapeutic use
Female
Genital Diseases, Female - drug therapy
Humans
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Summary:Cefuzonam (CZON, L-105), a cephem type antibiotic, was clinically studied in the field of obstetrics and gynecology. The results are summarized as follows: CZON 1-2 g was administered by injection twice daily to 11 cases of infections (4 of endometritis, 2 of pyometra, 3 of adnexitis and peritonitis, 1 of abdominal abscess, and 1 of puerperal fever). Clinical efficacy was excellent in 2 cases and good in 9 cases, with a very high overall efficacy rate of 100%. Slight elevations of GOT and GPT in 1 case were noted in clinical laboratory tests. No side effects attributable to the drug were noted. CZON is considered to be a useful drug for obstetric and gynecological infections.
ISSN:0368-2781
2186-5477
DOI:10.11553/antibiotics1968b.40.1617