MULTIPLE ORGAN FAILURE DUE TO CARDIOGENIC SHOCK IN NEWBORN INFANTS WITH SEVERE CARDIOVASCULAR MALFORMATIONS

• Published in: Japanese Journal of National Medical Services Vol. 55; no. 1; pp. 19 - 23
• Main Authors: OHTA, Akira, KAMBARA, Tamotsu, EGAWA, Yoshiyasu, KAWAHITO, Tomohisa, FURUKAWA, Seikyo
• Format: Journal Article
• Language: Japanese
• Published: Japanese Society of National Medical Services 20.02.2001
• Subjects: a congenital heart disease; hepatic necrosis; multiple organ failure; neonate; shock
• ISSN: 0021-1699; 1884-8729
• DOI: 10.11261/iryo1946.55.19

From January 1, 1984 to September 30, 1999, 22 neonates were admitted for circulatory collapse. They were divided into two period, 9 neonates were in the early stage, 1984-1991, 13 neonates were in the late stage, 1992-1999, In the newborn infants cardiac abnomalies of left ventricular outflow obstruction such as, hypoplastic left heart syndrome and interruption of the aortic arch were apt to progress shock following closure of the ductus arteriosus in the both period. In response to a severely reduced cardiac output, compensatory mechanics directed at restoring or redistributing blood flow. Consequently, various complication occured such as hepatic failure, renal failure, bleeding tendency, and hypoglycemia Nobody survived in early period. Six cases of 13 neonates survived and had normal development and growth except that one patient had a hearing loss. We shoud make efforts of preventing poor perfusion failure from irriversible organ failure.