Effects of drinking carbohydrate water during fasting on fluid balance and glucose metabolism a control study for healthy volunteer

• Published in: Jomyaku Keicho Eiyo Vol. 27; no. 6; pp. 1355 - 1359
• Main Authors: FUKUSHIMA, Hisashi, IWASAKA, Hideo, TANNO, Masaru, OHARA, Sayaka
• Format: Journal Article
• Language: Japanese
• Published: Japanese Society for Parenteral and Enteral Nutrition 2012
• Subjects: carbohydrate; ERAS; glyco-metabolism
• ISSN: 1344-4980; 1881-3623
• DOI: 10.11244/jjspen.27.1355

The effects of intake of carbohydrate water on fluid balance and glycometabolism were investigated in fasted healthy volunteers. Methods: Nine healthy volunteers drank 250 ml of carbohydrate water (ArgW) at 7:00 in the morning after abstinence from food from 21:00 and drink from 24:00 on the previous day. Another group of nine similarly fasted healthy volunteers did not drink carbohydrate water. Hematological tests for blood cell counts and electrolytes as indices of fluid balance, and glucose, free fatty acids (FFA), ketone bodies and insulin as measures of nutritional metabolism were conducted at 9:00 and 11:00 in all volunteers. Results: Intake of ArgW caused a significant blood dilution effect, but no change in electrolytes. ArgW also decreased glucose and FFA levels at two hours after intake, but increased glucose, FFA and ketone body levels at four hours after intake. Conclusion: Intake of carbohydrate water during fasting is effective for improving fluid balance, and the glucose content is actively used for improving glycometabolism. However, the effects may be limited and preoperative use of carbohydrate drinking water requires further investigation of the administration method and content.