Influence of Ocular Refraction Data With and Without Correction on Measurement with Optical Coherence Tomography

• Published in: JAPANESE ORTHOPTIC JOURNAL Vol. 46; pp. 187 - 195
• Main Authors: Kanenaga, Keisuke, Fujiwara, Atsushi, Sakate, Mio, Goto, Yasuhito, Inagaki, Asuka, Shiraga, Fumio
• Format: Journal Article
• Language: Japanese
• Published: JAPANESE ASSOCIATION OF CERTIFIED ORTHOPTISTS 2017
• Subjects: correction; ocular refraction data; optical coherence tomography (OCT); quantification; retinal thickness
• ISSN: 0387-5172; 1883-9215
• DOI: 10.4263/jorthoptic.046F120

[Purpose] To determine the influence of ocular refraction data (refractive error, corneal radius, and axial length) with and without correction on measurement for quantification and analysis of OCT images as well as the influential factors for the measurement.[Subjects and Methods] Subjects were 60 eyes (right) of 60 healthy volunteers (mean age, 38.7 ± 11.2 years) without a history of ocular diseases. Swept-Source Deep Range Imaging OCT-1 Atlantis (Topcon) was used for examination. Using the horizontal line scan protocol, measurements using ocular refraction data with and without correction were obtained. For quantification and analysis of the OCT images, the width of the image was measured with a built-in caliper and the measurements with and without data correction were compared.[Results] Mean refractive error, corneal radius, and axial length were -2.87 ± 2.92 D, 7.73 ± 0.21 mm, and 24.57 ± 1.33 mm, respectively. The respective mean measurements of width without and with data correction were 11986.0 μm and 12079.0 ± 795.0 μm and no significant difference was seen between the measurements (P = 0.61). The width difference significantly increased in eyes with refractive errors showing a tendency of myopia and longer axial length (refractive error and axial length, P < 0.01). Multivariable regression analysis using the width difference as the dependent variable and refractive error, corneal radius and axial length as the independent variables showed that axial length was an important determinant of the width difference (P < 0.01).[Conclusion] Ocular refraction data with and without correction influenced the measurement using the OCT images in eyes with long axial length.