A Case of Squamous Cell Carcinoma of the Anal Canal Associated with Ulcerative Colitis

The patient was diagnosed with ulcerative colitis (UC) of a left-sided colitis type at age 52. Surveillance colonoscopy at 59 showed a protruded lesion in the anal canal, and endoscopic biopsy revealed squamous cell carcinoma. While chemoradiotherapy is the first line treatment for squamous cell car...

Full description

Saved in:
Bibliographic Details
Published inThe Japanese Journal of Gastroenterological Surgery Vol. 54; no. 5; pp. 351 - 358
Main Authors Kawai, Kunihiko, Ogino, Takayuki, Matsui, Takahiro, Fujino, Shiki, Miyoshi, Norikatsu, Takahashi, Hidekazu, Uemura, Mamoru, Matsuda, Chu, Kushima, Ryoji, Mizushima, Tsunekazu, Doki, Yuichiro, Eguchi, Hidetoshi
Format Journal Article
LanguageJapanese
Published The Japanese Society of Gastroenterological Surgery 01.05.2021
Subjects
colitis-associated cancer
squamous cell carcinoma of the anal canal
ulcerative colitis
Online AccessGet full text

Cover

More Information
Summary:The patient was diagnosed with ulcerative colitis (UC) of a left-sided colitis type at age 52. Surveillance colonoscopy at 59 showed a protruded lesion in the anal canal, and endoscopic biopsy revealed squamous cell carcinoma. While chemoradiotherapy is the first line treatment for squamous cell carcinoma of the anal canal, in this case surgery was performed because of the risk of inflammatory exacerbation of the rectal-anal mucosa. Total proctocolectomy and ileal pouch anal anastomosis with ileostomy was performed at age 60. The histopathological diagnosis was pT2N1bM0 Stage IIIA. Twelve cycles of FOLFOX were administered as postoperative adjuvant chemotherapy. There was no recurrence in 8 months after surgery. We report this case as an example of squamous cell carcinoma of the anal canal associated with UC.
ISSN:0386-9768
1348-9372
DOI:10.5833/jjgs.2020.0047