B004: Gender differences in the clinical profile of complicated hypertensive patients seen in the hospital setting

• Published in: American journal of hypertension Vol. 13; no. S2; p. 55A
• Main Authors: Aranda-Granados, P., Aranda, F.J., Cansino, A., Aranda, P., Jimenez, Z., López de Novales, E.
• Format: Journal Article
• Language: English
• Published: Oxford Oxford University Press 01.04.2000
• Subjects: Arterial hypertension; cardiovascular risk; gender
• ISSN: 0895-7061; 1941-7225; 1879-1905
• DOI: 10.1016/S0895-7061(00)00432-5

Cardiovascular morbidity and mortality rates and causes differ from men to women. Looking at that direction we analyzed the clinical and therapeutic profile of 397 hypertensive patients derived to hospital due to one or more cardiovascular complications. The patients were 223(56,17%) men with a men age mean age 52,8±12 years, a mean BP (treated): 162,6±22 / 102±14 mmHg, HR: 78±13 b/min and BMI: 29±4.4 kg/m2 compared with 174(43,83) women with a mean age: 52,4±13 years, a mean BP: 170±30 / 101±16 mmHg, HR: 79±12, and BMI: 31,3±7. Associated C-V risk factors (%) (men vs women): Smoking (35,9/4,6)***; Diabetes (27,8/29,9); Dyslipidemie (44,9/44,3); Obesity (25,1/23). Ethiologic diagnosis (%) (men vs women): Essential HBP: (75,3/70,7); Renal HBP: (13,9/21,3); Renovascular: (6,28/5,75); Hyperaldosteronisms: (2,71/2,3). Cardiovascular complications (%) (men vs women): Stroke (20,6/20,7); IHD: (17,9/10,4)*; CHF: (3,6/8,1); CRF: (65,9/56,9). BP control (%) (men vs women): BP < 140/90: (2,69/8,10); DBP < 90 mmHg: (18,8/21,8). Use of antihypertensives (%) (men vs women): D: (43,9/37,9); BBs: (31,8/26,4); CCBs: (40,4/24,7)***; ACEIs: (55,6/52,3). Use of Statins (%): 7,2 in men and 1,15 in women***. In conclusions, although both group of patients showed a high prevalence of associated CV risk factors and a very poor BP control (even worse in men), men and women with complicated HBP differ because of the higher percentage of smokers among the former and the higher levels of systolic BP and BMI in the later. Theses differences may explain, at least in part, the higher frecuency of IHD, CRF and ischaemic strokes in men while women showed a greater frecuency of CHF and haemorrhagic strokes. (*) p< 0.05; (**) p < 0.01; (***) p < 0.001.