P-329: Cardiovascular morbid-mortality in hypertensive patients in relation to the presence of left ventricular hypertrophy. 11 years followed-up cohort

• Published in: American journal of hypertension Vol. 18; no. S4; p. 125A
• Main Authors: Vilaplana, Miguel, Dalfó, Antoni, Zabaleta, Edurne, Tovillas, Francisco J., Aragonès, Rosa, Benítez-Camps, Mencia
• Format: Journal Article
• Language: English
• Published: Oxford Oxford University Press 01.05.2005
• Subjects: Hypertension; Left Ventricular Hypertrophy; Primary Care
• ISSN: 0895-7061; 1941-7225; 1879-1905
• DOI: 10.1016/j.amjhyper.2005.03.347

Objectives: To Evaluate the frequency of cardiovascular events of a hypertensive patients cohort, in relation to the presence of left ventricular hypertrophy diagnosticated by echocardiogram, in Primary Care Attention. Design: Longitudinal study of one hypertensive patients followed-up from April 1993 to April 2004. Setting: Primary Attention. Urban health centre. Subjects: Sample of 265 (precision, 5%; alpha, 5%) hypertensive between 18 and 80 years, obtained by means of simple random. Criteria of exclusion: presence of previous cardiovascular disease. Methods and Interventions: The variables collected were: Presence of cardiovascular risk factors, age, sex, blood pressure, total and cHDL Colesterol, body mass index (BMI), time (months) from Hypertension diagnosis, electrocardiography left ventricular hypertrophy (LVH) criteria, left ventricular hypertrophy pattern. Cardiovasculars events recorded were: coronary heart disease, heart failure, arrhythmia, peripheral vascular disease, stroke. It has been used Chi-square and t Student or U- Mann Whitney test. Results: 63.8% (CI 95%: 58,0–69,6) had LVH, 63.3% of eccentric geometric pattern, and the rest the concentric one. Mean age was 66 years among patients with LVH (CI 95%: 65.2–67.8%), 71.6% (CI95%: 64.8-78.4) were women, Systolic Blood Pressure (SBP) mean was 161mmHg (CI 95%: 158,6-164,0), 13,6% (CI 95%:8,4–18,8) was smoker and 9,5% (CI 95%:5,5–14,9%) hads been smoker. 37,8% hypertensive with LVH had at least one cardiovascular event. The differents cardiovascular frequency events were: coronary heart disease 24,0%, arrhythmias 20,0%, stroke 19,0%, heart failure 19,0%, peripheral vascular disease 12,0%, and other cardiovascular events 6,0%. Patients with LVH were 5 years elder (p<0,004), SBP mean 6 mmHg higher (p=0,012) and women proportion over 17,3% (p=0,004), than hypertensive with no LVH. 25 patients died (16 with LVH) and 32.0% were relationated to cardiovascular cause. Conclusions: LVH is a recognised cardiovascular risk factor in hypertensive people with a high prevalence in our community, more over in elderly, women and higher SBP. Cardiovascular events are common in these patients. It is needed later measures and more analysis-for example the LV geometric patterns- in order to deepen on the special impact in our patients.