Silk stabilized graphene FET enzymatic glucose biosensor

This paper describes a silk fibroin-encapsulated graphene field effect transistor (FET) enzymatic biosensor that utilizes silk protein as both device substrate and enzyme immobilization material. Glucose molecules are detected by the conductance change and the Dirac point shift of the graphene trans...

Full description

Saved in:
Bibliographic Details
Published in2013 Transducers & Eurosensors XXVII: The 17th International Conference on Solid-State Sensors, Actuators and Microsystems (TRANSDUCERS & EUROSENSORS XXVII) pp. 2443 - 2446
Main Authors Xueqiu You, Pak, James Jungho
Format Conference Proceeding
LanguageEnglish
Published IEEE 01.06.2013
Subjects
Biochemistry
Biosensors
Electrodes
Enzyme stabilization
Field effect transistors
Glucose biosensor
Graphene
Graphene FET biosensor
Silk protein
Sugar
Online AccessGet full text

Cover

More Information
Summary:This paper describes a silk fibroin-encapsulated graphene field effect transistor (FET) enzymatic biosensor that utilizes silk protein as both device substrate and enzyme immobilization material. Glucose molecules are detected by the conductance change and the Dirac point shift of the graphene transistor as the glucose is oxidized by glucose oxidase that was immobilized in silk fibroin film on the graphene FET. This graphene FET biosensor detected glucose range in 3-10 mM, which covers the reference range for diabetes diagnostics. Because this fibroin-encapsulated graphene FET enzymatic biosensor is biocompatible, flexible, and long-term stable, it holds great promise for portable, wearable, and implantable continuous glucose monitoring applications.
ISSN:2159-547X
DOI:10.1109/Transducers.2013.6627300